node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1M1 | SDCCAG3 | ENSP00000388996 | ENSP00000349929 | adaptor-related protein complex 1, mu 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | serologically defined colon cancer antigen 3 | 0.749 |
AP1M1 | UBC | ENSP00000388996 | ENSP00000344818 | adaptor-related protein complex 1, mu 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | ubiquitin C | 0.866 |
CD99 | SDCCAG3 | ENSP00000370588 | ENSP00000349929 | CD99 molecule; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity) | serologically defined colon cancer antigen 3 | 0.573 |
CD99 | UBC | ENSP00000370588 | ENSP00000344818 | CD99 molecule; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity) | ubiquitin C | 0.620 |
GPSM1 | NKX2-3 | ENSP00000392828 | ENSP00000342828 | G-protein signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction | NK2 homeobox 3; Transcription factor (By similarity) | 0.440 |
GPSM1 | SDCCAG3 | ENSP00000392828 | ENSP00000349929 | G-protein signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction | serologically defined colon cancer antigen 3 | 0.483 |
GPSM1 | SLC9A4 | ENSP00000392828 | ENSP00000295269 | G-protein signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction | solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of [...] | 0.440 |
KIAA1468 | SDCCAG3 | ENSP00000381198 | ENSP00000349929 | KIAA1468 | serologically defined colon cancer antigen 3 | 0.472 |
KIAA1468 | UBC | ENSP00000381198 | ENSP00000344818 | KIAA1468 | ubiquitin C | 0.721 |
NKX2-3 | GPSM1 | ENSP00000342828 | ENSP00000392828 | NK2 homeobox 3; Transcription factor (By similarity) | G-protein signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction | 0.440 |
NKX2-3 | SDCCAG3 | ENSP00000342828 | ENSP00000349929 | NK2 homeobox 3; Transcription factor (By similarity) | serologically defined colon cancer antigen 3 | 0.487 |
NKX2-3 | SLC9A4 | ENSP00000342828 | ENSP00000295269 | NK2 homeobox 3; Transcription factor (By similarity) | solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of [...] | 0.459 |
PTPN13 | SDCCAG3 | ENSP00000394794 | ENSP00000349929 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | serologically defined colon cancer antigen 3 | 0.817 |
PTPN13 | UBC | ENSP00000394794 | ENSP00000344818 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | ubiquitin C | 0.498 |
SDCCAG3 | AP1M1 | ENSP00000349929 | ENSP00000388996 | serologically defined colon cancer antigen 3 | adaptor-related protein complex 1, mu 1 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.749 |
SDCCAG3 | CD99 | ENSP00000349929 | ENSP00000370588 | serologically defined colon cancer antigen 3 | CD99 molecule; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity) | 0.573 |
SDCCAG3 | GPSM1 | ENSP00000349929 | ENSP00000392828 | serologically defined colon cancer antigen 3 | G-protein signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction | 0.483 |
SDCCAG3 | KIAA1468 | ENSP00000349929 | ENSP00000381198 | serologically defined colon cancer antigen 3 | KIAA1468 | 0.472 |
SDCCAG3 | NKX2-3 | ENSP00000349929 | ENSP00000342828 | serologically defined colon cancer antigen 3 | NK2 homeobox 3; Transcription factor (By similarity) | 0.487 |
SDCCAG3 | PTPN13 | ENSP00000349929 | ENSP00000394794 | serologically defined colon cancer antigen 3 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.817 |