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STRINGSTRING
CSF2 CSF2 ZNRF4 ZNRF4 NCAM1 NCAM1 AGRN AGRN PTPRS PTPRS UBC UBC PPFIA3 PPFIA3 PPFIA1 PPFIA1 PPFIA4 PPFIA4 PPFIA2 PPFIA2 PPFIBP2 PPFIBP2
"PTPRS" - protein tyrosine phosphatase, receptor type, S in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
PTPRSprotein tyrosine phosphatase, receptor type, S; Interacts with LAR-interacting protein LIP.1 (1948 aa)    
Predicted Functional Partners:
PPFIA1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (1202 aa)
      score_image score_image   score_image   0.991
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (1257 aa)
      score_image score_image   score_image   0.927
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (1194 aa)
      score_image score_image   score_image   0.927
NCAM1
neural cell adhesion molecule 1 (848 aa)
          score_image score_image score_image 0.908
AGRN
agrin; Agrin N-terminal 110 kDa subunit- is involved in regulation of neurite outgrowth probably due to the presence of the glycosaminoglcan (GAG) side chains of heparan and chondroitin sulfate attached to the Ser/Thr- and Gly/Ser-rich regions. Also involved in modulation of growth factor signaling (By similarity) (2045 aa)
          score_image score_image   0.904
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (By similarity) (701 aa)
      score_image score_image   score_image   0.858
ZNRF4
zinc and ring finger 4 (429 aa)
            score_image   0.819
CSF2
colony stimulating factor 2 (granulocyte-macrophage); Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes (144 aa)
            score_image   0.800
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2); May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A (876 aa)
      score_image     score_image   0.759
UBC
ubiquitin C (685 aa)
        score_image       0.727
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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