node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP2B4 | CALM2 | ENSP00000350310 | ENSP00000272298 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | calmodulin 2 (phosphorylase kinase, delta) | 0.963 |
ATP2B4 | CD22 | ENSP00000350310 | ENSP00000085219 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | CD22 molecule | 0.849 |
ATP2B4 | DLG1 | ENSP00000350310 | ENSP00000345731 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | discs, large homolog 1 (Drosophila) | 0.864 |
ATP2B4 | NOS1 | ENSP00000350310 | ENSP00000337459 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | 0.917 |
ATP2B4 | PRKACA | ENSP00000350310 | ENSP00000309591 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | protein kinase, cAMP-dependent, catalytic, alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA, TRPC1 and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in th [...] | 0.800 |
ATP2B4 | PRKACB | ENSP00000350310 | ENSP00000359719 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | protein kinase, cAMP-dependent, catalytic, beta | 0.801 |
ATP2B4 | PRKACG | ENSP00000350310 | ENSP00000366488 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | protein kinase, cAMP-dependent, catalytic, gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus | 0.800 |
ATP2B4 | PRKG1 | ENSP00000350310 | ENSP00000363092 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | protein kinase, cGMP-dependent, type I; Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of t [...] | 0.800 |
ATP2B4 | PRKG2 | ENSP00000350310 | ENSP00000264399 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | protein kinase, cGMP-dependent, type II | 0.800 |
ATP2B4 | UBC | ENSP00000350310 | ENSP00000344818 | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | ubiquitin C | 0.928 |
CALM2 | ATP2B4 | ENSP00000272298 | ENSP00000350310 | calmodulin 2 (phosphorylase kinase, delta) | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.963 |
CALM2 | DLG1 | ENSP00000272298 | ENSP00000345731 | calmodulin 2 (phosphorylase kinase, delta) | discs, large homolog 1 (Drosophila) | 0.692 |
CALM2 | PRKACB | ENSP00000272298 | ENSP00000359719 | calmodulin 2 (phosphorylase kinase, delta) | protein kinase, cAMP-dependent, catalytic, beta | 0.432 |
CALM2 | UBC | ENSP00000272298 | ENSP00000344818 | calmodulin 2 (phosphorylase kinase, delta) | ubiquitin C | 0.978 |
CD22 | ATP2B4 | ENSP00000085219 | ENSP00000350310 | CD22 molecule | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.849 |
DLG1 | ATP2B4 | ENSP00000345731 | ENSP00000350310 | discs, large homolog 1 (Drosophila) | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.864 |
DLG1 | CALM2 | ENSP00000345731 | ENSP00000272298 | discs, large homolog 1 (Drosophila) | calmodulin 2 (phosphorylase kinase, delta) | 0.692 |
DLG1 | NOS1 | ENSP00000345731 | ENSP00000337459 | discs, large homolog 1 (Drosophila) | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | 0.693 |
DLG1 | UBC | ENSP00000345731 | ENSP00000344818 | discs, large homolog 1 (Drosophila) | ubiquitin C | 0.942 |
NOS1 | ATP2B4 | ENSP00000337459 | ENSP00000350310 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell | 0.917 |