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STRINGSTRING
METTL22 METTL22 METTL23 METTL23 METTL21A METTL21A METTL18 METTL18 GRWD1 GRWD1 METTL21C METTL21C METTL21B METTL21B METTL20 METTL20 HSPA1L HSPA1L HSPA5 HSPA5 HSPA8 HSPA8
"METTL20" - methyltransferase like 20 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL20methyltransferase like 20; Probable methyltransferase (By similarity) (262 aa)    
Predicted Functional Partners:
METTL21C
methyltransferase like 21C; Protein-lysine methyltransferase (264 aa)
            score_image   0.746
METTL23
methyltransferase like 23; Probable methyltransferase (By similarity) (190 aa)
            score_image   0.706
METTL21B
methyltransferase like 21B; Protein-lysine methyltransferase (By similarity) (226 aa)
            score_image   0.694
METTL22
methyltransferase like 22; Probable methyltransferase (By similarity) (404 aa)
            score_image   0.692
METTL18
methyltransferase like 18; Probable histidine methyltransferase (By similarity) (372 aa)
            score_image   0.671
GRWD1
glutamate-rich WD repeat containing 1 (446 aa)
            score_image   0.644
METTL21A
methyltransferase like 21A; Protein-lysine methyltransferase (218 aa)
            score_image   0.539
HSPA1L
heat shock 70kDa protein 1-like (641 aa)
            score_image   0.438
HSPA8
heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (646 aa)
        score_image   score_image   0.430
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER (654 aa)
        score_image   score_image   0.415
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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