MCTP2 protein (Homo sapiens) - STRING network view

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Score

MCTP2

multiple C2 domains, transmembrane 2 (878 aa)

Predicted Functional Partners:

ARRDC4

0.681

ARRDC3

0.609

ARRDC2

0.448

PCSK1

0.447

RGMA

0.415

CHD2

0.405

ASB7

0.402

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRDC2	MCTP2	ENSP00000222250	ENSP00000350377	arrestin domain containing 2	multiple C2 domains, transmembrane 2	0.448
ARRDC3	MCTP2	ENSP00000265138	ENSP00000350377	arrestin domain containing 3	multiple C2 domains, transmembrane 2	0.609
ARRDC3	PCSK1	ENSP00000265138	ENSP00000308024	arrestin domain containing 3	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	0.559
ARRDC4	MCTP2	ENSP00000268042	ENSP00000350377	arrestin domain containing 4	multiple C2 domains, transmembrane 2	0.681
ARRDC4	PCSK1	ENSP00000268042	ENSP00000308024	arrestin domain containing 4	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	0.453
ASB7	MCTP2	ENSP00000328327	ENSP00000350377	ankyrin repeat and SOCS box containing 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity)	multiple C2 domains, transmembrane 2	0.402
CHD2	MCTP2	ENSP00000377747	ENSP00000350377	chromodomain helicase DNA binding protein 2; Sequence-selective DNA-binding protein (By similarity)	multiple C2 domains, transmembrane 2	0.405
MCTP2	ARRDC2	ENSP00000350377	ENSP00000222250	multiple C2 domains, transmembrane 2	arrestin domain containing 2	0.448
MCTP2	ARRDC3	ENSP00000350377	ENSP00000265138	multiple C2 domains, transmembrane 2	arrestin domain containing 3	0.609
MCTP2	ARRDC4	ENSP00000350377	ENSP00000268042	multiple C2 domains, transmembrane 2	arrestin domain containing 4	0.681
MCTP2	ASB7	ENSP00000350377	ENSP00000328327	multiple C2 domains, transmembrane 2	ankyrin repeat and SOCS box containing 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity)	0.402
MCTP2	CHD2	ENSP00000350377	ENSP00000377747	multiple C2 domains, transmembrane 2	chromodomain helicase DNA binding protein 2; Sequence-selective DNA-binding protein (By similarity)	0.405
MCTP2	PCSK1	ENSP00000350377	ENSP00000308024	multiple C2 domains, transmembrane 2	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	0.447
MCTP2	RGMA	ENSP00000350377	ENSP00000452126	multiple C2 domains, transmembrane 2	RGM domain family, member A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivati [...]	0.415
PCSK1	ARRDC3	ENSP00000308024	ENSP00000265138	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	arrestin domain containing 3	0.559
PCSK1	ARRDC4	ENSP00000308024	ENSP00000268042	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	arrestin domain containing 4	0.453
PCSK1	MCTP2	ENSP00000308024	ENSP00000350377	proprotein convertase subtilisin/kexin type 1; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin	multiple C2 domains, transmembrane 2	0.447
RGMA	MCTP2	ENSP00000452126	ENSP00000350377	RGM domain family, member A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivati [...]	multiple C2 domains, transmembrane 2	0.415

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