TUSC1 protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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TUSC1

tumor suppressor candidate 1 (212 aa)

Predicted Functional Partners:

IFNW1

0.537

FAM118A

0.532

OR1J1

0.509

PRR23A

0.507

CCDC9

0.472

KLHL9

0.450

IFNA6

0.420

OCEL1

0.416

IFNE

0.407

CENPW

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC9	CENPW	ENSP00000221922	ENSP00000357311	coiled-coil domain containing 9	centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...]	0.426
CCDC9	OCEL1	ENSP00000221922	ENSP00000215061	coiled-coil domain containing 9	occludin/ELL domain containing 1	0.471
CCDC9	PRR23A	ENSP00000221922	ENSP00000372649	coiled-coil domain containing 9	proline rich 23A	0.537
CCDC9	TUSC1	ENSP00000221922	ENSP00000350716	coiled-coil domain containing 9	tumor suppressor candidate 1	0.472
CENPW	CCDC9	ENSP00000357311	ENSP00000221922	centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...]	coiled-coil domain containing 9	0.426
CENPW	PRR23A	ENSP00000357311	ENSP00000372649	centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...]	proline rich 23A	0.480
CENPW	TUSC1	ENSP00000357311	ENSP00000350716	centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...]	tumor suppressor candidate 1	0.404
FAM118A	OR1J1	ENSP00000216214	ENSP00000259357	family with sequence similarity 118, member A	olfactory receptor, family 1, subfamily J, member 1; Odorant receptor (Potential)	0.586
FAM118A	TUSC1	ENSP00000216214	ENSP00000350716	family with sequence similarity 118, member A	tumor suppressor candidate 1	0.532
IFNA6	KLHL9	ENSP00000369558	ENSP00000351933	interferon, alpha 6; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes- a protein kinase and an oligoadenylate synthetase	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	0.502
IFNA6	TUSC1	ENSP00000369558	ENSP00000350716	interferon, alpha 6; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes- a protein kinase and an oligoadenylate synthetase	tumor suppressor candidate 1	0.420
IFNE	KLHL9	ENSP00000418018	ENSP00000351933	interferon, epsilon	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	0.407
IFNE	TUSC1	ENSP00000418018	ENSP00000350716	interferon, epsilon	tumor suppressor candidate 1	0.407
IFNW1	KLHL9	ENSP00000369578	ENSP00000351933	interferon, omega 1	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	0.700
IFNW1	TUSC1	ENSP00000369578	ENSP00000350716	interferon, omega 1	tumor suppressor candidate 1	0.537
KLHL9	IFNA6	ENSP00000351933	ENSP00000369558	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	interferon, alpha 6; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes- a protein kinase and an oligoadenylate synthetase	0.502
KLHL9	IFNE	ENSP00000351933	ENSP00000418018	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	interferon, epsilon	0.407
KLHL9	IFNW1	ENSP00000351933	ENSP00000369578	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	interferon, omega 1	0.700
KLHL9	TUSC1	ENSP00000351933	ENSP00000350716	kelch-like 9 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis	tumor suppressor candidate 1	0.450
OCEL1	CCDC9	ENSP00000215061	ENSP00000221922	occludin/ELL domain containing 1	coiled-coil domain containing 9	0.471

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