node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAGE1 | MPPED2 | ENSP00000425493 | ENSP00000350833 | cancer antigen 1 | metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) | 0.543 |
DCDC5 | DNAJC24 | ENSP00000389792 | ENSP00000417548 | doublecortin domain containing 5 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | 0.758 |
DCDC5 | ELP4 | ENSP00000389792 | ENSP00000298937 | doublecortin domain containing 5 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | 0.753 |
DCDC5 | IMMP1L | ENSP00000389792 | ENSP00000278200 | doublecortin domain containing 5 | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.752 |
DCDC5 | MPPED2 | ENSP00000389792 | ENSP00000350833 | doublecortin domain containing 5 | metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) | 0.757 |
DCDC5 | PAX6 | ENSP00000389792 | ENSP00000368401 | doublecortin domain containing 5 | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.517 |
DNAJC24 | DCDC5 | ENSP00000417548 | ENSP00000389792 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | doublecortin domain containing 5 | 0.758 |
DNAJC24 | ELP4 | ENSP00000417548 | ENSP00000298937 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | 0.754 |
DNAJC24 | IMMP1L | ENSP00000417548 | ENSP00000278200 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.779 |
DNAJC24 | MPPED2 | ENSP00000417548 | ENSP00000350833 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) | 0.757 |
DNAJC24 | PAX6 | ENSP00000417548 | ENSP00000368401 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.519 |
ELP4 | DCDC5 | ENSP00000298937 | ENSP00000389792 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | doublecortin domain containing 5 | 0.753 |
ELP4 | DNAJC24 | ENSP00000298937 | ENSP00000417548 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | 0.754 |
ELP4 | IMMP1L | ENSP00000298937 | ENSP00000278200 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | 0.749 |
ELP4 | MPPED2 | ENSP00000298937 | ENSP00000350833 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) | 0.752 |
ELP4 | PAX6 | ENSP00000298937 | ENSP00000368401 | elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.609 |
FSHB | MPPED2 | ENSP00000254122 | ENSP00000350833 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) | 0.561 |
FSHB | PAX6 | ENSP00000254122 | ENSP00000368401 | follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs | paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes | 0.561 |
IMMP1L | DCDC5 | ENSP00000278200 | ENSP00000389792 | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | doublecortin domain containing 5 | 0.752 |
IMMP1L | DNAJC24 | ENSP00000278200 | ENSP00000417548 | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO | DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) | 0.779 |