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STRINGSTRING
VPS29 VPS29 FSHB FSHB CAGE1 CAGE1 PAX6 PAX6 MPPED2 MPPED2 DCDC5 DCDC5 PLS3 PLS3 DNAJC24 DNAJC24 ELP4 ELP4 ITM2A ITM2A IMMP1L IMMP1L
"MPPED2" - metallophosphoesterase domain containing 2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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fusion edge
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gene co-occurrence
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protein homology
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MPPED2metallophosphoesterase domain containing 2; Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system (By similarity) (294 aa)    
Predicted Functional Partners:
DNAJC24
DnaJ (Hsp40) homolog, subfamily C, member 24; Stimulates the ATPase activity of several Hsp70-type chaperones (By similarity) (149 aa)
            score_image   0.757
DCDC5
doublecortin domain containing 5 (354 aa)
            score_image   0.757
ELP4
elongator acetyltransferase complex subunit 4; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4 (424 aa)
            score_image   0.752
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (166 aa)
            score_image   0.751
PAX6
paired box 6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes (436 aa)
            score_image   0.653
PLS3
plastin 3; Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia (630 aa)
            score_image   0.620
ITM2A
integral membrane protein 2A (263 aa)
            score_image   0.615
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae); Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (186 aa)
            score_image   0.614
FSHB
follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermatogenesis in the reproductive organs (129 aa)
            score_image   0.561
CAGE1
cancer antigen 1 (839 aa)
        score_image       0.543
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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