node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRIX1 | KRR1 | ENSP00000338862 | ENSP00000229214 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | KRR1, small subunit (SSU) processome component, homolog (yeast); Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity) | 0.914 |
BRIX1 | NOA1 | ENSP00000338862 | ENSP00000264230 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP | 0.442 |
BRIX1 | ZNF346 | ENSP00000338862 | ENSP00000350869 | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.481 |
HBS1L | MT-CO1 | ENSP00000356811 | ENSP00000354499 | HBS1-like (S. cerevisiae) | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | 0.532 |
HBS1L | ZNF346 | ENSP00000356811 | ENSP00000350869 | HBS1-like (S. cerevisiae) | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.499 |
ILF3 | STAU2 | ENSP00000404121 | ENSP00000428756 | interleukin enhancer binding factor 3, 90kDa | staufen, RNA binding protein, homolog 2 (Drosophila) | 0.497 |
ILF3 | XPO5 | ENSP00000404121 | ENSP00000265351 | interleukin enhancer binding factor 3, 90kDa | exportin 5 | 0.989 |
ILF3 | ZNF346 | ENSP00000404121 | ENSP00000350869 | interleukin enhancer binding factor 3, 90kDa | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.913 |
KRR1 | BRIX1 | ENSP00000229214 | ENSP00000338862 | KRR1, small subunit (SSU) processome component, homolog (yeast); Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity) | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.914 |
KRR1 | ZNF346 | ENSP00000229214 | ENSP00000350869 | KRR1, small subunit (SSU) processome component, homolog (yeast); Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity) | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.502 |
MT-CO1 | HBS1L | ENSP00000354499 | ENSP00000356811 | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | HBS1-like (S. cerevisiae) | 0.532 |
MT-CO1 | ZNF346 | ENSP00000354499 | ENSP00000350869 | mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.866 |
NOA1 | BRIX1 | ENSP00000264230 | ENSP00000338862 | nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP | BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); Required for biogenesis of the 60S ribosomal subunit | 0.442 |
NOA1 | ZNF346 | ENSP00000264230 | ENSP00000350869 | nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.499 |
PARK2 | ZNF346 | ENSP00000355865 | ENSP00000350869 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.581 |
STAU2 | ILF3 | ENSP00000428756 | ENSP00000404121 | staufen, RNA binding protein, homolog 2 (Drosophila) | interleukin enhancer binding factor 3, 90kDa | 0.497 |
STAU2 | ZNF346 | ENSP00000428756 | ENSP00000350869 | staufen, RNA binding protein, homolog 2 (Drosophila) | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.481 |
TARBP2 | XPO5 | ENSP00000266987 | ENSP00000265351 | TAR (HIV-1) RNA binding protein 2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interferin [...] | exportin 5 | 0.981 |
TARBP2 | ZNF346 | ENSP00000266987 | ENSP00000350869 | TAR (HIV-1) RNA binding protein 2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interferin [...] | zinc finger protein 346; Binds to dsRNA and DNA (By similarity) | 0.603 |
XPO5 | ILF3 | ENSP00000265351 | ENSP00000404121 | exportin 5 | interleukin enhancer binding factor 3, 90kDa | 0.989 |