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STRINGSTRING
SLC32A1 SLC32A1 ALDH7A1 ALDH7A1 RELN RELN ALDH9A1 ALDH9A1 GAD1 GAD1 ABAT ABAT CAD CAD ALDH1A3 ALDH1A3 ALDH4A1 ALDH4A1 GLS GLS GLUL GLUL
"GAD1" - glutamate decarboxylase 1 (brain, 67kDa) in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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GAD1glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)    
Predicted Functional Partners:
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
score_image     score_image score_image score_image score_image   0.987
ALDH7A1
aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
      score_image score_image score_image score_image   0.979
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
      score_image score_image score_image score_image   0.969
RELN
reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity) (3460 aa)
            score_image   0.948
GLS
glutaminase; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity (669 aa)
score_image     score_image   score_image score_image   0.946
GLUL
glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts (373 aa)
          score_image score_image   0.942
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1; Involved in the uptake of GABA and glycine into the synaptic vesicles (525 aa)
      score_image     score_image   0.932
ALDH1A3
aldehyde dehydrogenase 1 family, member A3; Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity) (512 aa)
      score_image score_image score_image score_image   0.928
ALDH9A1
aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
      score_image score_image score_image score_image   0.928
ALDH4A1
aldehyde dehydrogenase 4 family, member A1 (563 aa)
      score_image score_image score_image score_image   0.927
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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