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STRINGSTRING
PHACTR3 PHACTR3 BCAS2 BCAS2 BCAS3 BCAS3 ZNF217 ZNF217 ACSF2 ACSF2 BCAS4 BCAS4 ZFP64 ZFP64 USP32 USP32 RSBN1 RSBN1 DEPDC1B DEPDC1B FAM190A FAM190A
"BCAS4" - breast carcinoma amplified sequence 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCAS4breast carcinoma amplified sequence 4 (211 aa)    
Predicted Functional Partners:
BCAS3
breast carcinoma amplified sequence 3 (928 aa)
            score_image   0.867
PHACTR3
phosphatase and actin regulator 3 (559 aa)
            score_image   0.601
USP32
ubiquitin specific peptidase 32 (1604 aa)
            score_image   0.533
ZFP64
zinc finger protein 64 homolog (mouse); May be involved in transcriptional regulation (681 aa)
            score_image   0.520
ACSF2
acyl-CoA synthetase family member 2; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipodyte differentiation (615 aa)
            score_image   0.504
RSBN1
round spermatid basic protein 1 (802 aa)
            score_image   0.495
ZNF217
zinc finger protein 217; Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at ’Ser-473’ (1048 aa)
            score_image   0.487
FAM190A
family with sequence similarity 190, member A (900 aa)
            score_image   0.480
BCAS2
breast carcinoma amplified sequence 2; Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (225 aa)
            score_image   0.477
DEPDC1B
DEP domain containing 1B (529 aa)
            score_image   0.464
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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