node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM114A1 | PPAT | ENSP00000351740 | ENSP00000264220 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | phosphoribosyl pyrophosphate amidotransferase | 0.463 |
FAM114A1 | RAB2A | ENSP00000351740 | ENSP00000262646 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.543 |
FAM114A1 | RAB2B | ENSP00000351740 | ENSP00000380869 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | RAB2B, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential) | 0.543 |
FAM114A1 | RSU1 | ENSP00000351740 | ENSP00000339521 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | 0.538 |
FAM114A1 | SEC24D | ENSP00000351740 | ENSP00000280551 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | SEC24 family, member D (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex | 0.636 |
FAM114A1 | SPG21 | ENSP00000351740 | ENSP00000204566 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | spastic paraplegia 21 (autosomal recessive, Mast syndrome); May play a role as a negative regulatory factor in CD4- dependent T-cell activation | 0.447 |
FAM114A1 | THUMPD3 | ENSP00000351740 | ENSP00000339532 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | THUMP domain containing 3 | 0.491 |
FAM114A1 | TLN1 | ENSP00000351740 | ENSP00000316029 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | talin 1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity) | 0.524 |
FAM114A1 | UBC | ENSP00000351740 | ENSP00000344818 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | ubiquitin C | 0.620 |
FAM114A1 | UROS | ENSP00000351740 | ENSP00000357775 | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme) | 0.491 |
PPAT | FAM114A1 | ENSP00000264220 | ENSP00000351740 | phosphoribosyl pyrophosphate amidotransferase | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | 0.463 |
PPAT | RSU1 | ENSP00000264220 | ENSP00000339521 | phosphoribosyl pyrophosphate amidotransferase | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | 0.538 |
PPAT | UBC | ENSP00000264220 | ENSP00000344818 | phosphoribosyl pyrophosphate amidotransferase | ubiquitin C | 0.896 |
RAB2A | FAM114A1 | ENSP00000262646 | ENSP00000351740 | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | 0.543 |
RAB2A | UBC | ENSP00000262646 | ENSP00000344818 | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | ubiquitin C | 0.949 |
RAB2B | FAM114A1 | ENSP00000380869 | ENSP00000351740 | RAB2B, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential) | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | 0.543 |
RAB2B | UBC | ENSP00000380869 | ENSP00000344818 | RAB2B, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential) | ubiquitin C | 0.541 |
RSU1 | FAM114A1 | ENSP00000339521 | ENSP00000351740 | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | family with sequence similarity 114, member A1; May play a role in neuronal cell development (By similarity) | 0.538 |
RSU1 | PPAT | ENSP00000339521 | ENSP00000264220 | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | phosphoribosyl pyrophosphate amidotransferase | 0.538 |
RSU1 | SEC24D | ENSP00000339521 | ENSP00000280551 | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | SEC24 family, member D (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex | 0.491 |