Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | C17orf80 | chromosome 17 open reading frame 80 (609 aa) | ||||||||||||
Predicted Functional Partners:
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 | C1orf212 | chromosome 1 open reading frame 212 (92 aa) |
 |
0.585 | ||||||||||
 | WDR73 | WD repeat domain 73 (378 aa) |
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0.499 | ||||||||||
 | IQCE | IQ motif containing E (695 aa) |
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0.450 | ||||||||||
 | ENSG00000248919 | ATP5J2-PTCD1 readthrough (749 aa) |
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0.420 | ||||||||||
 | FAM127B | family with sequence similarity 127, member B (113 aa) |
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0.412 | ||||||||||
 | DMKN | dermokine (476 aa) |
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0.410 | ||||||||||
 | TMEM108 | transmembrane protein 108 (575 aa) |
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0.407 | ||||||||||
 | MRPS24 | mitochondrial ribosomal protein S24 (167 aa) |
|
0.407 | ||||||||||
 | EFCAB4A | EF-hand calcium binding domain 4A; Plays a role in store-operated Ca(2+) entry (SOCE) (294 aa) |
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0.406 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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