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CACNB3 CACNB3 CACNB1 CACNB1 CACNA1S CACNA1S CACNA1D CACNA1D CACNB4 CACNB4 CACNA1C CACNA1C CACNA1I CACNA1I CACNB2 CACNB2 CACNA1G CACNA1G LEF1 LEF1 CTNNB1 CTNNB1
"CACNA1G" - calcium channel, voltage-dependent, T type, alpha 1G subunit in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit (2377 aa)    
Predicted Functional Partners:
LEF1
lymphoid enhancer-binding factor 1; Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 [...] (399 aa)
           score_image score_image   0.978
CACNB2
calcium channel, voltage-dependent, beta 2 subunit (660 aa)
           score_image score_image   0.942
CACNB1
calcium channel, voltage-dependent, beta 1 subunit; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting (598 aa)
           score_image score_image   0.941
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit (2186 aa)
           score_image score_image score_image 0.932
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the ’high-voltage activated’ (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and b [...] (2181 aa)
           score_image score_image score_image 0.931
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the ’high-voltage activated’ (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and b [...] (1873 aa)
           score_image score_image score_image 0.930
CACNB4
calcium channel, voltage-dependent, beta 4 subunit; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting (520 aa)
           score_image score_image   0.926
CACNB3
calcium channel, voltage-dependent, beta 3 subunit; The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting (484 aa)
           score_image score_image   0.925
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit (2223 aa)
         score_image score_image score_image score_image 0.916
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation [...] (781 aa)
           score_image score_image   0.915
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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