| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABHD15 | SLC2A10 | ENSP00000302657 | ENSP00000352216 | abhydrolase domain containing 15 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.527 |
| ACOT8 | SLC2A10 | ENSP00000217455 | ENSP00000352216 | acyl-CoA thioesterase 8; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA- amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxi [...] | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.558 |
| ACOT8 | TP53RK | ENSP00000217455 | ENSP00000361186 | acyl-CoA thioesterase 8; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA- amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxi [...] | TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation | 0.616 |
| AP3B1 | SLC2A10 | ENSP00000255194 | ENSP00000352216 | adaptor-related protein complex 3, beta 1 subunit; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required [...] | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.505 |
| AP3B2 | SLC2A10 | ENSP00000261722 | ENSP00000352216 | adaptor-related protein complex 3, beta 2 subunit; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required [...] | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.505 |
| ENSG00000251357 | SLC2A10 | ENSP00000400325 | ENSP00000352216 | Uncharacterized protein | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.552 |
| P4HA3 | SLC2A10 | ENSP00000332170 | ENSP00000352216 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.497 |
| PTGIS | SLC2A10 | ENSP00000244043 | ENSP00000352216 | prostaglandin I2 (prostacyclin) synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2) | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.698 |
| SLC28A2 | SLC2A10 | ENSP00000315006 | ENSP00000352216 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | 0.504 |
| SLC2A10 | ABHD15 | ENSP00000352216 | ENSP00000302657 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | abhydrolase domain containing 15 | 0.527 |
| SLC2A10 | ACOT8 | ENSP00000352216 | ENSP00000217455 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | acyl-CoA thioesterase 8; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA- amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxi [...] | 0.558 |
| SLC2A10 | AP3B1 | ENSP00000352216 | ENSP00000255194 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | adaptor-related protein complex 3, beta 1 subunit; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required [...] | 0.505 |
| SLC2A10 | AP3B2 | ENSP00000352216 | ENSP00000261722 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | adaptor-related protein complex 3, beta 2 subunit; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required [...] | 0.505 |
| SLC2A10 | ENSG00000251357 | ENSP00000352216 | ENSP00000400325 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | Uncharacterized protein | 0.552 |
| SLC2A10 | P4HA3 | ENSP00000352216 | ENSP00000332170 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.497 |
| SLC2A10 | PTGIS | ENSP00000352216 | ENSP00000244043 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | prostaglandin I2 (prostacyclin) synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2) | 0.698 |
| SLC2A10 | SLC28A2 | ENSP00000352216 | ENSP00000315006 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues | 0.504 |
| SLC2A10 | TP53RK | ENSP00000352216 | ENSP00000361186 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation | 0.592 |
| SLC2A10 | UGGT1 | ENSP00000352216 | ENSP00000259253 | solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter | UDP-glucose glycoprotein glucosyltransferase 1; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation | 0.600 |
| TP53RK | ACOT8 | ENSP00000361186 | ENSP00000217455 | TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation | acyl-CoA thioesterase 8; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA- amino acid N- acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxi [...] | 0.616 |
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