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HADH HADH EHHADH EHHADH HIBADH HIBADH HADHA HADHA HIBCH HIBCH METTL17 METTL17 MRPS2 MRPS2 MRPS35 MRPS35 MRPS10 MRPS10 MRPS9 MRPS9 DAP3 DAP3
"HIBCH" - 3-hydroxyisobutyryl-CoA hydrolase in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
HIBCH3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)    
Predicted Functional Partners:
HIBADH
3-hydroxyisobutyrate dehydrogenase (336 aa)
  score_image   score_image   score_image score_image   0.986
HADH
hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA (331 aa)
score_image     score_image   score_image score_image   0.965
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
score_image     score_image   score_image score_image score_image 0.952
MRPS9
mitochondrial ribosomal protein S9 (396 aa)
      score_image score_image       0.951
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa)
score_image     score_image   score_image score_image score_image 0.951
MRPS2
mitochondrial ribosomal protein S2 (296 aa)
        score_image       0.950
DAP3
death associated protein 3; Involved in mediating interferon-gamma-induced cell death (398 aa)
      score_image score_image       0.946
MRPS10
mitochondrial ribosomal protein S10 (201 aa)
      score_image score_image       0.946
MRPS35
mitochondrial ribosomal protein S35 (323 aa)
      score_image score_image       0.944
METTL17
methyltransferase like 17; May be a component of the mitochondrial small ribosomal subunit (By similarity) (478 aa)
        score_image       0.942
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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