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CALM2 CALM2 MYH10 MYH10 ACTB ACTB UBC UBC EXOC4 EXOC4 ARPC2 ARPC2 MYO1C MYO1C EXOC7 EXOC7 ACTR2 ACTR2 SLC2A4 SLC2A4 ARPC3 ARPC3
"MYO1C" - myosin IC in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
MYO1Cmyosin IC; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell’s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of ve [...] (1063 aa)    
Predicted Functional Partners:
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4; Insulin-regulated facilitative glucose transporter (509 aa)
          score_image score_image   0.996
ACTB
actin, beta (375 aa)
        score_image score_image score_image   0.982
CALM2
calmodulin 2 (phosphorylase kinase, delta) (149 aa)
        score_image   score_image   0.979
MYH10
myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (1976 aa)
        score_image   score_image score_image 0.976
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.972
ACTR2
ARP2 actin-related protein 2 homolog (yeast); Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (399 aa)
        score_image score_image score_image   0.964
EXOC4
exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (By similarity) (974 aa)
        score_image score_image score_image   0.954
EXOC7
exocyst complex component 7 (735 aa)
        score_image score_image score_image   0.953
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (178 aa)
        score_image score_image score_image   0.952
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (300 aa)
        score_image score_image score_image   0.949
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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