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STRINGSTRING
BZW2 BZW2 TYW5 TYW5 HSFY2 HSFY2 BZW1 BZW1 HSFY1 HSFY1 C2orf69 C2orf69 KCTD18 KCTD18 SCN5A SCN5A KCTD14 KCTD14 KCTD19 KCTD19 KCTD2 KCTD2
"KCTD18" - potassium channel tetramerisation domain containing 18 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
KCTD18potassium channel tetramerisation domain containing 18 (426 aa)    
Predicted Functional Partners:
TYW5
tRNA-yW synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes (315 aa)
            score_image   0.796
C2orf69
chromosome 2 open reading frame 69 (385 aa)
            score_image   0.740
HSFY2
heat shock transcription factor, Y linked 2 (401 aa)
            score_image   0.677
BZW1
basic leucine zipper and W2 domains 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly (451 aa)
            score_image   0.637
KCTD19
potassium channel tetramerisation domain containing 19 (926 aa)
            score_image   0.635
HSFY1
heat shock transcription factor, Y-linked 1 (401 aa)
            score_image   0.602
KCTD14
potassium channel tetramerisation domain containing 14 (255 aa)
            score_image   0.555
SCN5A
sodium channel, voltage-gated, type V, alpha subunit (2016 aa)
            score_image   0.501
BZW2
basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity) (419 aa)
            score_image   0.485
KCTD2
potassium channel tetramerisation domain containing 2 (263 aa)
            score_image   0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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