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STRINGSTRING
GNAS GNAS OR2L2 OR2L2 ADCY1 ADCY1 PTH PTH ENSG00000254995 ENSG00000254995 LPPR3 LPPR3 DPH2 DPH2 ARID3A ARID3A XAB2 XAB2 CAMSAP3 CAMSAP3 DIRAS1 DIRAS1
"LPPR3" - hsa-mir-3187 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Neighborhood
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
LPPR3hsa-mir-3187 (746 aa)    
Predicted Functional Partners:
ADCY1
adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning (1119 aa)
            score_image   0.721
DIRAS1
DIRAS family, GTP-binding RAS-like 1; Displays low GTPase activity and exist predominantly in the GTP-bound form (198 aa)
            score_image   0.601
ARID3A
AT rich interactive domain 3A (BRIGHT-like); Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation (593 aa)
            score_image   0.572
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3; Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site (1276 aa)
            score_image   0.560
ENSG00000254995
STX16-NPEPL1 readthrough (non-protein coding) (382 aa)
            score_image   0.560
DPH2
DPH2 homolog (S. cerevisiae); Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (By similarity) (489 aa)
            score_image   0.503
GNAS
GNAS complex locus; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase- it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms (By similarity) (1037 aa)
            score_image   0.485
OR2L2
olfactory receptor, family 2, subfamily L, member 2; Odorant receptor (Potential) (312 aa)
            score_image   0.456
XAB2
XPA binding protein 2; Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (855 aa)
            score_image   0.454
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells (115 aa)
            score_image   0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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