SDF4 protein (Homo sapiens) - STRING network view

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SDF4

stromal cell derived factor 4 (362 aa)

Predicted Functional Partners:

PVALB

0.871

STXBP2

0.815

CALB2

0.813

UBC

0.762

USP12

0.740

STXBP1

0.739

S100G

0.700

S100B

0.633

STXBP3

0.619

AIF1

0.581

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	S100B	ENSP00000365227	ENSP00000291700	allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	0.472
AIF1	SDF4	ENSP00000365227	ENSP00000353094	allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation	stromal cell derived factor 4	0.581
AIF1	UBC	ENSP00000365227	ENSP00000344818	allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation	ubiquitin C	0.488
CALB2	PVALB	ENSP00000307508	ENSP00000216200	calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	0.943
CALB2	SDF4	ENSP00000307508	ENSP00000353094	calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons	stromal cell derived factor 4	0.813
CALB2	UBC	ENSP00000307508	ENSP00000344818	calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons	ubiquitin C	0.415
PVALB	CALB2	ENSP00000216200	ENSP00000307508	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons	0.943
PVALB	S100B	ENSP00000216200	ENSP00000291700	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	0.424
PVALB	S100G	ENSP00000216200	ENSP00000369547	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	S100 calcium binding protein G	0.562
PVALB	SDF4	ENSP00000216200	ENSP00000353094	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	stromal cell derived factor 4	0.871
S100B	AIF1	ENSP00000291700	ENSP00000365227	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation	0.472
S100B	PVALB	ENSP00000291700	ENSP00000216200	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	0.424
S100B	SDF4	ENSP00000291700	ENSP00000353094	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	stromal cell derived factor 4	0.633
S100G	PVALB	ENSP00000369547	ENSP00000216200	S100 calcium binding protein G	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	0.562
S100G	SDF4	ENSP00000369547	ENSP00000353094	S100 calcium binding protein G	stromal cell derived factor 4	0.700
SDF4	AIF1	ENSP00000353094	ENSP00000365227	stromal cell derived factor 4	allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation	0.581
SDF4	CALB2	ENSP00000353094	ENSP00000307508	stromal cell derived factor 4	calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons	0.813
SDF4	PVALB	ENSP00000353094	ENSP00000216200	stromal cell derived factor 4	parvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions	0.871
SDF4	S100B	ENSP00000353094	ENSP00000291700	stromal cell derived factor 4	S100 calcium binding protein B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). C [...]	0.633
SDF4	S100G	ENSP00000353094	ENSP00000369547	stromal cell derived factor 4	S100 calcium binding protein G	0.700

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