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PRKAR1B PRKAR1B AKAP1 AKAP1 PRKACG PRKACG ADCY9 ADCY9 PRKAR1A PRKAR1A PRKACA PRKACA ADCY7 ADCY7 PRKACB PRKACB ADCY5 ADCY5 ADCY8 ADCY8 ADCY6 ADCY6
"PRKAR1B" - protein kinase, cAMP-dependent, regulatory, type I, beta in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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experimentally determined
Predicted Interactions
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textmining
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co-expression
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protein homology
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PRKAR1Bprotein kinase, cAMP-dependent, regulatory, type I, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells (381 aa)    
Predicted Functional Partners:
PRKACB
protein kinase, cAMP-dependent, catalytic, beta (398 aa)
  score_image   score_image score_image score_image score_image   0.999
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA, TRPC1 and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in th [...] (351 aa)
  score_image   score_image score_image score_image score_image   0.998
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus (351 aa)
  score_image   score_image score_image score_image score_image   0.994
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells (381 aa)
        score_image score_image score_image score_image 0.980
ADCY9
adenylate cyclase 9; May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity) (1353 aa)
score_image       score_image score_image score_image   0.972
AKAP1
A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane (903 aa)
        score_image score_image score_image   0.971
ADCY8
adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) (1251 aa)
score_image     score_image score_image score_image score_image   0.971
ADCY6
adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) (1168 aa)
score_image     score_image score_image score_image score_image   0.970
ADCY5
adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1261 aa)
score_image     score_image score_image score_image score_image   0.969
ADCY7
adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1080 aa)
score_image     score_image score_image score_image score_image   0.969
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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