GSTCD protein (Homo sapiens) - STRING network view

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GSTCD

glutathione S-transferase, C-terminal domain containing (633 aa)

Predicted Functional Partners:

ABL1

0.802

THSD4

0.569

FAM13A

0.564

HHIP

0.538

HTR4

0.507

ARHGEF38

0.480

ADAM19

0.474

PID1

0.472

INTS12

0.472

LRRC16B

0.459

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	GSTCD	ENSP00000361423	ENSP00000353695	c-abl oncogene 1, non-receptor tyrosine kinase; Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN ( [...]	glutathione S-transferase, C-terminal domain containing	0.802
ADAM19	GSTCD	ENSP00000257527	ENSP00000353695	ADAM metallopeptidase domain 19; Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity)	glutathione S-transferase, C-terminal domain containing	0.474
ARHGEF38	GSTCD	ENSP00000416125	ENSP00000353695	Rho guanine nucleotide exchange factor (GEF) 38; May act as a guanine-nucleotide releasing factor (By similarity)	glutathione S-transferase, C-terminal domain containing	0.480
FAM13A	GSTCD	ENSP00000264344	ENSP00000353695	family with sequence similarity 13, member A	glutathione S-transferase, C-terminal domain containing	0.564
FAM13A	HHIP	ENSP00000264344	ENSP00000296575	family with sequence similarity 13, member A	hedgehog interacting protein; Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family	0.632
GSTCD	ABL1	ENSP00000353695	ENSP00000361423	glutathione S-transferase, C-terminal domain containing	c-abl oncogene 1, non-receptor tyrosine kinase; Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT and PXN ( [...]	0.802
GSTCD	ADAM19	ENSP00000353695	ENSP00000257527	glutathione S-transferase, C-terminal domain containing	ADAM metallopeptidase domain 19; Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity)	0.474
GSTCD	ARHGEF38	ENSP00000353695	ENSP00000416125	glutathione S-transferase, C-terminal domain containing	Rho guanine nucleotide exchange factor (GEF) 38; May act as a guanine-nucleotide releasing factor (By similarity)	0.480
GSTCD	FAM13A	ENSP00000353695	ENSP00000264344	glutathione S-transferase, C-terminal domain containing	family with sequence similarity 13, member A	0.564
GSTCD	HHIP	ENSP00000353695	ENSP00000296575	glutathione S-transferase, C-terminal domain containing	hedgehog interacting protein; Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family	0.538
GSTCD	HTR4	ENSP00000353695	ENSP00000353915	glutathione S-transferase, C-terminal domain containing	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	0.507
GSTCD	INTS12	ENSP00000353695	ENSP00000340737	glutathione S-transferase, C-terminal domain containing	integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes	0.472
GSTCD	LRRC16B	ENSP00000353695	ENSP00000340467	glutathione S-transferase, C-terminal domain containing	leucine rich repeat containing 16B	0.459
GSTCD	PID1	ENSP00000353695	ENSP00000375907	glutathione S-transferase, C-terminal domain containing	phosphotyrosine interaction domain containing 1; Increases proliferation of preadipocytes without affecting adipocytic differentiation	0.472
GSTCD	THSD4	ENSP00000353695	ENSP00000261862	glutathione S-transferase, C-terminal domain containing	thrombospondin, type I, domain containing 4; Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN (By similarity)	0.569
HHIP	FAM13A	ENSP00000296575	ENSP00000264344	hedgehog interacting protein; Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family	family with sequence similarity 13, member A	0.632
HHIP	GSTCD	ENSP00000296575	ENSP00000353695	hedgehog interacting protein; Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family	glutathione S-transferase, C-terminal domain containing	0.538
HTR4	GSTCD	ENSP00000353915	ENSP00000353695	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	glutathione S-transferase, C-terminal domain containing	0.507
INTS12	GSTCD	ENSP00000340737	ENSP00000353695	integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes	glutathione S-transferase, C-terminal domain containing	0.472
LRRC16B	GSTCD	ENSP00000340467	ENSP00000353695	leucine rich repeat containing 16B	glutathione S-transferase, C-terminal domain containing	0.459

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