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STRINGSTRING
TBL3 TBL3 UBC UBC FRG1B FRG1B CCDC144A CCDC144A FBXW10 FBXW10 FAM182B FAM182B PABPC1L2B PABPC1L2B PABPC1L2A PABPC1L2A AQP12B AQP12B
"CCDC144A" - coiled-coil domain containing 144A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC144Acoiled-coil domain containing 144A (1427 aa)    
Predicted Functional Partners:
FRG1B
FSHD region gene 1 family, member B (182 aa)
            score_image   0.702
FAM182B
family with sequence similarity 182, member B (152 aa)
            score_image   0.700
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B (200 aa)
            score_image   0.631
PABPC1L2A
poly(A) binding protein, cytoplasmic 1-like 2A (200 aa)
            score_image   0.631
UBC
ubiquitin C (685 aa)
        score_image       0.551
TBL3
transducin (beta)-like 3 (808 aa)
            score_image   0.507
FBXW10
F-box and WD repeat domain containing 10; Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (1051 aa)
            score_image   0.472
AQP12B
aquaporin 12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) (307 aa)
            score_image   0.457
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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