node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B4GALT1 | FUT8 | ENSP00000369055 | ENSP00000353910 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | 0.934 |
B4GALT1 | FUT9 | ENSP00000369055 | ENSP00000302599 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | 0.921 |
B4GALT2 | FUT8 | ENSP00000310696 | ENSP00000353910 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | 0.918 |
B4GALT2 | FUT9 | ENSP00000310696 | ENSP00000302599 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | 0.906 |
B4GALT2 | MGAT4B | ENSP00000310696 | ENSP00000338487 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosy [...] | 0.483 |
B4GALT3 | FUT8 | ENSP00000320965 | ENSP00000353910 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | 0.910 |
B4GALT3 | FUT9 | ENSP00000320965 | ENSP00000302599 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | 0.900 |
FUT8 | B4GALT1 | ENSP00000353910 | ENSP00000369055 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.934 |
FUT8 | B4GALT2 | ENSP00000353910 | ENSP00000310696 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.918 |
FUT8 | B4GALT3 | ENSP00000353910 | ENSP00000320965 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | 0.910 |
FUT8 | FUT9 | ENSP00000353910 | ENSP00000302599 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | 0.804 |
FUT8 | KDR | ENSP00000353910 | ENSP00000263923 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | kinase insert domain receptor (a type III receptor tyrosine kinase); Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an importan [...] | 0.800 |
FUT8 | MGAT2 | ENSP00000353910 | ENSP00000307423 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; Catalyzes an essential step in the conversion of oligo- mannose to complex N-glycans | 0.953 |
FUT8 | MGAT3 | ENSP00000353910 | ENSP00000345270 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase; It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides | 0.974 |
FUT8 | MGAT4A | ENSP00000353910 | ENSP00000264968 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells | 0.942 |
FUT8 | MGAT4B | ENSP00000353910 | ENSP00000338487 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosy [...] | 0.940 |
FUT8 | MYC | ENSP00000353910 | ENSP00000367207 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity) | v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes | 0.800 |
FUT9 | B4GALT1 | ENSP00000302599 | ENSP00000369055 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.921 |
FUT9 | B4GALT2 | ENSP00000302599 | ENSP00000310696 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.906 |
FUT9 | B4GALT3 | ENSP00000302599 | ENSP00000320965 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase); Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids | 0.900 |