node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRB2 | AVP | ENSP00000305372 | ENSP00000369647 | adrenoceptor beta 2, surface | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | 0.906 |
ADRB2 | CRH | ENSP00000305372 | ENSP00000276571 | adrenoceptor beta 2, surface | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | 0.904 |
ADRB2 | GCG | ENSP00000305372 | ENSP00000387662 | adrenoceptor beta 2, surface | glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life | 0.911 |
ADRB2 | GIP | ENSP00000305372 | ENSP00000350005 | adrenoceptor beta 2, surface | gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion | 0.900 |
ADRB2 | GIPR | ENSP00000305372 | ENSP00000467494 | adrenoceptor beta 2, surface | gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | 0.903 |
ADRB2 | HTR4 | ENSP00000305372 | ENSP00000353915 | adrenoceptor beta 2, surface | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled | 0.958 |
ADRB2 | NPS | ENSP00000305372 | ENSP00000381105 | adrenoceptor beta 2, surface | neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity) | 0.917 |
ADRB2 | POMC | ENSP00000305372 | ENSP00000264708 | adrenoceptor beta 2, surface | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.917 |
ADRB2 | VIP | ENSP00000305372 | ENSP00000356213 | adrenoceptor beta 2, surface | vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder | 0.901 |
AVP | ADRB2 | ENSP00000369647 | ENSP00000305372 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | adrenoceptor beta 2, surface | 0.906 |
AVP | CRH | ENSP00000369647 | ENSP00000276571 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | 0.997 |
AVP | GCG | ENSP00000369647 | ENSP00000387662 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life | 0.963 |
AVP | GIP | ENSP00000369647 | ENSP00000350005 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | gastric inhibitory polypeptide; Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion | 0.934 |
AVP | GIPR | ENSP00000369647 | ENSP00000467494 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | gastric inhibitory polypeptide receptor; This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | 0.921 |
AVP | HTR4 | ENSP00000369647 | ENSP00000353915 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled | 0.929 |
AVP | NPS | ENSP00000369647 | ENSP00000381105 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity) | 0.980 |
AVP | POMC | ENSP00000369647 | ENSP00000264708 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.987 |
AVP | VIP | ENSP00000369647 | ENSP00000356213 | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | vasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder | 0.963 |
CRH | ADRB2 | ENSP00000276571 | ENSP00000305372 | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | adrenoceptor beta 2, surface | 0.904 |
CRH | AVP | ENSP00000276571 | ENSP00000369647 | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | arginine vasopressin; Neurophysin 2 specifically binds vasopressin | 0.997 |