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STRINGSTRING
DICER1 DICER1 MAP1LC3A MAP1LC3A GRIA2 GRIA2 WWP2 WWP2 ADARB1 ADARB1 ADAT3 ADAT3 SYCP2 SYCP2 SYCP3 SYCP3 ABI3 ABI3 POFUT2 POFUT2 COL18A1 COL18A1
"ADARB1" - adenosine deaminase, RNA-specific, B1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
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experimentally determined
Predicted Interactions
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fusion edge
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gene co-occurrence
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textmining
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co-expression
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protein homology
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ADARB1adenosine deaminase, RNA-specific, B1 (741 aa)    
Predicted Functional Partners:
SYCP2
synaptonemal complex protein 2; Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity) (1530 aa)
            score_image   0.810
ABI3
ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility (366 aa)
      score_image     score_image   0.809
POFUT2
protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...] (429 aa)
            score_image   0.801
SYCP3
synaptonemal complex protein 3; Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity) (236 aa)
            score_image   0.745
DICER1
dicer 1, ribonuclease type III; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering [...] (1922 aa)
            score_image   0.723
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa)
        score_image       0.665
COL18A1
collagen, type XVIII, alpha 1 (1519 aa)
            score_image   0.659
ADAT3
adenosine deaminase, tRNA-specific 3 (351 aa)
            score_image   0.640
WWP2
WW domain containing E3 ubiquitin protein ligase 2 (870 aa)
        score_image   score_image   0.625
GRIA2
glutamate receptor, ionotropic, AMPA 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized [...] (883 aa)
            score_image   0.617
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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