node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABI3 | ADARB1 | ENSP00000225941 | ENSP00000353920 | ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility | adenosine deaminase, RNA-specific, B1 | 0.809 |
ADARB1 | ABI3 | ENSP00000353920 | ENSP00000225941 | adenosine deaminase, RNA-specific, B1 | ABI family, member 3; May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility | 0.809 |
ADARB1 | ADAT3 | ENSP00000353920 | ENSP00000332448 | adenosine deaminase, RNA-specific, B1 | adenosine deaminase, tRNA-specific 3 | 0.640 |
ADARB1 | COL18A1 | ENSP00000353920 | ENSP00000347665 | adenosine deaminase, RNA-specific, B1 | collagen, type XVIII, alpha 1 | 0.659 |
ADARB1 | DICER1 | ENSP00000353920 | ENSP00000343745 | adenosine deaminase, RNA-specific, B1 | dicer 1, ribonuclease type III; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering [...] | 0.723 |
ADARB1 | GRIA2 | ENSP00000353920 | ENSP00000264426 | adenosine deaminase, RNA-specific, B1 | glutamate receptor, ionotropic, AMPA 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized [...] | 0.617 |
ADARB1 | MAP1LC3A | ENSP00000353920 | ENSP00000363970 | adenosine deaminase, RNA-specific, B1 | microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) | 0.665 |
ADARB1 | POFUT2 | ENSP00000353920 | ENSP00000339613 | adenosine deaminase, RNA-specific, B1 | protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...] | 0.801 |
ADARB1 | SYCP2 | ENSP00000353920 | ENSP00000350162 | adenosine deaminase, RNA-specific, B1 | synaptonemal complex protein 2; Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity) | 0.810 |
ADARB1 | SYCP3 | ENSP00000353920 | ENSP00000266743 | adenosine deaminase, RNA-specific, B1 | synaptonemal complex protein 3; Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity) | 0.745 |
ADARB1 | WWP2 | ENSP00000353920 | ENSP00000348283 | adenosine deaminase, RNA-specific, B1 | WW domain containing E3 ubiquitin protein ligase 2 | 0.625 |
ADAT3 | ADARB1 | ENSP00000332448 | ENSP00000353920 | adenosine deaminase, tRNA-specific 3 | adenosine deaminase, RNA-specific, B1 | 0.640 |
COL18A1 | ADARB1 | ENSP00000347665 | ENSP00000353920 | collagen, type XVIII, alpha 1 | adenosine deaminase, RNA-specific, B1 | 0.659 |
COL18A1 | POFUT2 | ENSP00000347665 | ENSP00000339613 | collagen, type XVIII, alpha 1 | protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...] | 0.687 |
DICER1 | ADARB1 | ENSP00000343745 | ENSP00000353920 | dicer 1, ribonuclease type III; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering [...] | adenosine deaminase, RNA-specific, B1 | 0.723 |
GRIA2 | ADARB1 | ENSP00000264426 | ENSP00000353920 | glutamate receptor, ionotropic, AMPA 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized [...] | adenosine deaminase, RNA-specific, B1 | 0.617 |
MAP1LC3A | ADARB1 | ENSP00000363970 | ENSP00000353920 | microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) | adenosine deaminase, RNA-specific, B1 | 0.665 |
POFUT2 | ADARB1 | ENSP00000339613 | ENSP00000353920 | protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...] | adenosine deaminase, RNA-specific, B1 | 0.801 |
POFUT2 | COL18A1 | ENSP00000339613 | ENSP00000347665 | protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...] | collagen, type XVIII, alpha 1 | 0.687 |
SYCP2 | ADARB1 | ENSP00000350162 | ENSP00000353920 | synaptonemal complex protein 2; Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements (By similarity) | adenosine deaminase, RNA-specific, B1 | 0.810 |