Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | CYB561 | cytochrome b-561; Secretory vesicle-specific electron transport protein (251 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | FRRS1 | ferric-chelate reductase 1; Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm (By similarity) (626 aa) |
 |
0.890 | ||||||||||
 | PAM | peptidylglycine alpha-amidating monooxygenase (974 aa) |
|
0.810 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
|
0.730 | ||||||||||
 | DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase); Conversion of dopamine to noradrenaline (617 aa) |
|
0.673 | ||||||||||
 | EDA | ectodysplasin A (391 aa) |
|
0.516 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
Share
