node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EMR1 | ITGAX | ENSP00000311545 | ENSP00000268296 | egf-like module containing, mucin-like, hormone receptor-like 1 | integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis | 0.612 |
EMR1 | SIGLEC14 | ENSP00000311545 | ENSP00000354090 | egf-like module containing, mucin-like, hormone receptor-like 1 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.483 |
IL22RA2 | SIGLEC14 | ENSP00000296980 | ENSP00000354090 | interleukin 22 receptor, alpha 2; Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.576 |
IL22RA2 | SIRPA | ENSP00000296980 | ENSP00000348307 | interleukin 22 receptor, alpha 2; Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses | signal-regulatory protein alpha | 0.576 |
ITGAX | EMR1 | ENSP00000268296 | ENSP00000311545 | integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.612 |
ITGAX | SIGLEC14 | ENSP00000268296 | ENSP00000354090 | integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.483 |
ITGAX | TYROBP | ENSP00000268296 | ENSP00000262629 | integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis | TYRO protein tyrosine kinase binding protein; Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin | 0.457 |
MDGA2 | SIGLEC14 | ENSP00000382178 | ENSP00000354090 | MAM domain containing glycosylphosphatidylinositol anchor 2; May involved in cell-cell interactions (By similarity) | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.963 |
OR7D2 | SIGLEC14 | ENSP00000345563 | ENSP00000354090 | olfactory receptor, family 7, subfamily D, member 2; Odorant receptor (Potential) | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.636 |
SIGLEC11 | SIGLEC14 | ENSP00000412361 | ENSP00000354090 | sialic acid binding Ig-like lectin 11; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | 0.907 |
SIGLEC11 | SIGLEC15 | ENSP00000412361 | ENSP00000374125 | sialic acid binding Ig-like lectin 11; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules | sialic acid binding Ig-like lectin 15; Binds sialylated glycoproteins | 0.908 |
SIGLEC11 | ST3GAL3 | ENSP00000412361 | ENSP00000262915 | sialic acid binding Ig-like lectin 11; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.738 |
SIGLEC11 | TYROBP | ENSP00000412361 | ENSP00000262629 | sialic acid binding Ig-like lectin 11; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules | TYRO protein tyrosine kinase binding protein; Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin | 0.943 |
SIGLEC14 | EMR1 | ENSP00000354090 | ENSP00000311545 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.483 |
SIGLEC14 | IL22RA2 | ENSP00000354090 | ENSP00000296980 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | interleukin 22 receptor, alpha 2; Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses | 0.576 |
SIGLEC14 | ITGAX | ENSP00000354090 | ENSP00000268296 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis | 0.483 |
SIGLEC14 | MDGA2 | ENSP00000354090 | ENSP00000382178 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | MAM domain containing glycosylphosphatidylinositol anchor 2; May involved in cell-cell interactions (By similarity) | 0.963 |
SIGLEC14 | OR7D2 | ENSP00000354090 | ENSP00000345563 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | olfactory receptor, family 7, subfamily D, member 2; Odorant receptor (Potential) | 0.636 |
SIGLEC14 | SIGLEC11 | ENSP00000354090 | ENSP00000412361 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | sialic acid binding Ig-like lectin 11; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8- linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules | 0.907 |
SIGLEC14 | SIGLEC15 | ENSP00000354090 | ENSP00000374125 | sialic acid binding Ig-like lectin 14; Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors | sialic acid binding Ig-like lectin 15; Binds sialylated glycoproteins | 0.903 |