FAM107A protein (Homo sapiens) - STRING network view

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FAM107A

family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development (144 aa)

Predicted Functional Partners:

USHBP1

0.592

KRT15

0.551

LDOC1

0.512

SHOC2

0.490

PPP2R3A

0.482

PPP2R2A

0.482

MYO15B

0.414

PPP2R3B

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM107A	KRT15	ENSP00000354270	ENSP00000254043	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	keratin 15	0.551
FAM107A	LDOC1	ENSP00000354270	ENSP00000359557	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers	0.512
FAM107A	MYO15B	ENSP00000354270	ENSP00000293201	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	myosin XVB pseudogene	0.414
FAM107A	PPP2R2A	ENSP00000354270	ENSP00000325074	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.482
FAM107A	PPP2R3A	ENSP00000354270	ENSP00000264977	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	protein phosphatase 2, regulatory subunit B’’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.482
FAM107A	PPP2R3B	ENSP00000354270	ENSP00000375080	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	protein phosphatase 2, regulatory subunit B’’, beta; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.404
FAM107A	SHOC2	ENSP00000354270	ENSP00000358464	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	soc-2 suppressor of clear homolog (C. elegans); Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the ’Ser-259’ inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes	0.490
FAM107A	USHBP1	ENSP00000354270	ENSP00000252597	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	Usher syndrome 1C binding protein 1	0.592
KRT15	FAM107A	ENSP00000254043	ENSP00000354270	keratin 15	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	0.551
KRT15	LDOC1	ENSP00000254043	ENSP00000359557	keratin 15	leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers	0.590
KRT15	USHBP1	ENSP00000254043	ENSP00000252597	keratin 15	Usher syndrome 1C binding protein 1	0.426
LDOC1	FAM107A	ENSP00000359557	ENSP00000354270	leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	0.512
LDOC1	KRT15	ENSP00000359557	ENSP00000254043	leucine zipper, down-regulated in cancer 1; May have an important role in the development and/or progression of some cancers	keratin 15	0.590
MYO15B	FAM107A	ENSP00000293201	ENSP00000354270	myosin XVB pseudogene	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	0.414
PPP2R2A	FAM107A	ENSP00000325074	ENSP00000354270	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	0.482
PPP2R2A	PPP2R3A	ENSP00000325074	ENSP00000264977	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	protein phosphatase 2, regulatory subunit B’’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.975
PPP2R2A	PPP2R3B	ENSP00000325074	ENSP00000375080	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	protein phosphatase 2, regulatory subunit B’’, beta; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.919
PPP2R2A	SHOC2	ENSP00000325074	ENSP00000358464	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	soc-2 suppressor of clear homolog (C. elegans); Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the ’Ser-259’ inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes	0.900
PPP2R3A	FAM107A	ENSP00000264977	ENSP00000354270	protein phosphatase 2, regulatory subunit B’’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	family with sequence similarity 107, member A; When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development	0.482
PPP2R3A	PPP2R2A	ENSP00000264977	ENSP00000325074	protein phosphatase 2, regulatory subunit B’’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment	0.975

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