Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
HTR4 HTR4 TSPEAR TSPEAR ABCA13 ABCA13 CUX2 CUX2 SLC4A4 SLC4A4 CCDC17 CCDC17 FAM109A FAM109A NOP2 NOP2 INPP5B INPP5B OCRL OCRL C15orf32 C15orf32
"FAM109A" - family with sequence similarity 109, member A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM109Afamily with sequence similarity 109, member A; Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane (262 aa)    
Predicted Functional Partners:
OCRL
oculocerebrorenal syndrome of Lowe (901 aa)
        score_image   score_image   0.865
INPP5B
inositol polyphosphate-5-phosphatase, 75kDa (913 aa)
        score_image   score_image   0.715
CUX2
cut-like homeobox 2; May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner (By similarity) (1486 aa)
            score_image   0.681
TSPEAR
thrombospondin-type laminin G domain and EAR repeats; May play a role in development or function of the auditory system (669 aa)
            score_image   0.662
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4 (1094 aa)
            score_image   0.606
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled (428 aa)
            score_image   0.561
CCDC17
coiled-coil domain containing 17 (622 aa)
            score_image   0.539
NOP2
NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase (808 aa)
            score_image   0.529
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13 (5058 aa)
            score_image   0.515
C15orf32
chromosome 15 open reading frame 32 (178 aa)
            score_image   0.514
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (42%)