Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KEAP1 | TSC22D2 | ENSP00000171111 | ENSP00000354543 | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | TSC22 domain family, member 2 | 0.570 |
| KEAP1 | UBC | ENSP00000171111 | ENSP00000344818 | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | ubiquitin C | 0.999 |
| LDLRAD4 | TSC22D2 | ENSP00000352420 | ENSP00000354543 | low density lipoprotein receptor class A domain containing 4 | TSC22 domain family, member 2 | 0.471 |
| LHX3 | TSC22D2 | ENSP00000360811 | ENSP00000354543 | LIM homeobox 3; Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 | TSC22 domain family, member 2 | 0.651 |
| LHX4 | TSC22D2 | ENSP00000263726 | ENSP00000354543 | LIM homeobox 4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung (By similarity) | TSC22 domain family, member 2 | 0.689 |
| TIGD2 | TSC22D2 | ENSP00000317170 | ENSP00000354543 | tigger transposable element derived 2 | TSC22 domain family, member 2 | 0.465 |
| TSC22D2 | KEAP1 | ENSP00000354543 | ENSP00000171111 | TSC22 domain family, member 2 | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | 0.570 |
| TSC22D2 | LDLRAD4 | ENSP00000354543 | ENSP00000352420 | TSC22 domain family, member 2 | low density lipoprotein receptor class A domain containing 4 | 0.471 |
| TSC22D2 | LHX3 | ENSP00000354543 | ENSP00000360811 | TSC22 domain family, member 2 | LIM homeobox 3; Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 | 0.651 |
| TSC22D2 | LHX4 | ENSP00000354543 | ENSP00000263726 | TSC22 domain family, member 2 | LIM homeobox 4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung (By similarity) | 0.689 |
| TSC22D2 | TIGD2 | ENSP00000354543 | ENSP00000317170 | TSC22 domain family, member 2 | tigger transposable element derived 2 | 0.465 |
| TSC22D2 | UBC | ENSP00000354543 | ENSP00000344818 | TSC22 domain family, member 2 | ubiquitin C | 0.483 |
| TSC22D2 | ZNF286B | ENSP00000354543 | ENSP00000461413 | TSC22 domain family, member 2 | zinc finger protein 286B; May be involved in transcriptional regulation (By similarity) | 0.407 |
| UBC | KEAP1 | ENSP00000344818 | ENSP00000171111 | ubiquitin C | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | 0.999 |
| UBC | TSC22D2 | ENSP00000344818 | ENSP00000354543 | ubiquitin C | TSC22 domain family, member 2 | 0.483 |
| UBC | ZNF286B | ENSP00000344818 | ENSP00000461413 | ubiquitin C | zinc finger protein 286B; May be involved in transcriptional regulation (By similarity) | 0.416 |
| ZNF286B | TSC22D2 | ENSP00000461413 | ENSP00000354543 | zinc finger protein 286B; May be involved in transcriptional regulation (By similarity) | TSC22 domain family, member 2 | 0.407 |
| ZNF286B | UBC | ENSP00000461413 | ENSP00000344818 | zinc finger protein 286B; May be involved in transcriptional regulation (By similarity) | ubiquitin C | 0.416 |
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