Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | MRPL21 | mitochondrial ribosomal protein L21 (205 aa) | ||||||||||||
Predicted Functional Partners:
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 | MRPL38 | mitochondrial ribosomal protein L38 (380 aa) |
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0.991 | ||||||||
 | MRPL51 | mitochondrial ribosomal protein L51 (128 aa) |
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0.973 | ||||||||
 | MRPL24 | mitochondrial ribosomal protein L24 (216 aa) |
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0.951 | |||||||||
 | MRPL40 | mitochondrial ribosomal protein L40 (206 aa) |
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0.942 | |||||||||
 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) |
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0.927 | |||||||||
 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) |
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0.925 | |||||||||
 | MRPS9 | mitochondrial ribosomal protein S9 (396 aa) |
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0.917 | ||||||||
 | UBC | ubiquitin C (685 aa) |
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0.721 | ||||||||||
 | TPCN2 | two pore segment channel 2; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction (752 aa) |
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0.712 | ||||||||||
 | DNAJC19 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) (116 aa) |
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0.679 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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