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STRINGSTRING
PC PC IARS2 IARS2 MTHFD1 MTHFD1 CALU CALU CDH2 CDH2 SARS2 SARS2 PPT2 PPT2 SUPT5H SUPT5H MRPL49 MRPL49 NENF NENF MRPL23 MRPL23
"PPT2" - palmitoyl-protein thioesterase 2 in Homo sapiens
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
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protein homology
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Score
PPT2palmitoyl-protein thioesterase 2 (308 aa)    
Predicted Functional Partners:
PC
pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (1178 aa)
        score_image       0.972
SARS2
seryl-tRNA synthetase 2, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) (520 aa)
        score_image   score_image   0.969
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial (1012 aa)
        score_image       0.969
CDH2
cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) (906 aa)
        score_image       0.955
NENF
neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) (172 aa)
        score_image       0.913
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae); Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promot [...] (1087 aa)
        score_image       0.904
MTHFD1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (935 aa)
        score_image       0.903
MRPL49
mitochondrial ribosomal protein L49 (166 aa)
        score_image   score_image   0.898
CALU
calumenin (323 aa)
        score_image   score_image   0.893
MRPL23
mitochondrial ribosomal protein L23 (153 aa)
        score_image       0.862
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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