FCRL5 protein (Homo sapiens) - STRING network view

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FCRL5

Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells (977 aa)

Predicted Functional Partners:

BCR

0.824

BCL9

0.750

PIGR

0.749

MUC1

0.495

SULT2B1

0.485

RFXANK

0.481

CD3E

0.476

CD3G

0.463

HRAS

0.410

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	FCRL5	ENSP00000234739	ENSP00000354691	B-cell CLL/lymphoma 9	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	0.750
BCL9	HRAS	ENSP00000234739	ENSP00000309845	B-cell CLL/lymphoma 9	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	0.461
BCR	FCRL5	ENSP00000303507	ENSP00000354691	breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	0.824
BCR	HRAS	ENSP00000303507	ENSP00000309845	breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	0.512
CD3E	CD3G	ENSP00000354566	ENSP00000431445	CD3e molecule, epsilon (CD3-TCR complex); The CD3 complex mediates signal transduction	CD3g molecule, gamma (CD3-TCR complex); The CD3 complex mediates signal transduction	0.998
CD3E	FCRL5	ENSP00000354566	ENSP00000354691	CD3e molecule, epsilon (CD3-TCR complex); The CD3 complex mediates signal transduction	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	0.476
CD3G	CD3E	ENSP00000431445	ENSP00000354566	CD3g molecule, gamma (CD3-TCR complex); The CD3 complex mediates signal transduction	CD3e molecule, epsilon (CD3-TCR complex); The CD3 complex mediates signal transduction	0.998
CD3G	FCRL5	ENSP00000431445	ENSP00000354691	CD3g molecule, gamma (CD3-TCR complex); The CD3 complex mediates signal transduction	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	0.463
FCRL5	BCL9	ENSP00000354691	ENSP00000234739	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	B-cell CLL/lymphoma 9	0.750
FCRL5	BCR	ENSP00000354691	ENSP00000303507	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity	0.824
FCRL5	CD3E	ENSP00000354691	ENSP00000354566	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	CD3e molecule, epsilon (CD3-TCR complex); The CD3 complex mediates signal transduction	0.476
FCRL5	CD3G	ENSP00000354691	ENSP00000431445	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	CD3g molecule, gamma (CD3-TCR complex); The CD3 complex mediates signal transduction	0.463
FCRL5	HRAS	ENSP00000354691	ENSP00000309845	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	0.410
FCRL5	MUC1	ENSP00000354691	ENSP00000357380	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	mucin 1, cell surface associated	0.495
FCRL5	PIGR	ENSP00000354691	ENSP00000348888	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment	0.749
FCRL5	RFXANK	ENSP00000354691	ENSP00000305071	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	regulatory factor X-associated ankyrin-containing protein; Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes	0.481
FCRL5	SULT2B1	ENSP00000354691	ENSP00000201586	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol	0.485
HRAS	BCL9	ENSP00000309845	ENSP00000234739	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	B-cell CLL/lymphoma 9	0.461
HRAS	BCR	ENSP00000309845	ENSP00000303507	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity	0.512
HRAS	FCRL5	ENSP00000309845	ENSP00000354691	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity	Fc receptor-like 5; May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells	0.410

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