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SLC4A5 SLC4A5 SLC4A2 SLC4A2 NALCN NALCN SLC4A10 SLC4A10 FOXI1 FOXI1 SLC26A1 SLC26A1 SLC13A4 SLC13A4 PAPSS1 PAPSS1 SLC4A4 SLC4A4 PAPSS2 PAPSS2 SLC13A1 SLC13A1
"SLC26A1" - solute carrier family 26 (sulfate transporter), member 1 in Homo sapiens
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Predicted Interactions
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SLC26A1solute carrier family 26 (sulfate transporter), member 1; High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate (701 aa)    
Predicted Functional Partners:
PAPSS2
3’-phosphoadenosine 5’-phosphosulfate synthase 2; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5’-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3’-phosphoadenylylsulfate (PAPS- activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. May have a important [...] (619 aa)
      score_image   score_image score_image   0.962
PAPSS1
3’-phosphoadenosine 5’-phosphosulfate synthase 1; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5’-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3’-phosphoadenylylsulfate (PAPS- activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Also involved in the [...] (624 aa)
      score_image   score_image score_image   0.947
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney (595 aa)
            score_image   0.755
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4 (1094 aa)
            score_image   0.619
SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1); Plasma membrane anion exchange protein of wide distribution (1241 aa)
            score_image   0.605
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5; Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+)-HCO3(-) stoichiometry of 2-1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+)-HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH (1137 aa)
            score_image   0.538
NALCN
sodium leak channel, non-selective; Voltage-independent, cation-nonselective channel which is permeable to sodium, potassium and calcium ions. Responsible for the background sodium ion leak current in neurons and controls neuronal excitability. Activated either by neuropeptides substance P or neurotensin. Required for normal respiratory rhythm and neonatal survival (By similarity) (1738 aa)
            score_image   0.538
SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10; Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role in regulating intracellular pH (By similarity) (1118 aa)
            score_image   0.536
SLC13A4
solute carrier family 13 (sodium/sulfate symporters), member 4; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV) (626 aa)
            score_image   0.518
FOXI1
forkhead box I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity) (378 aa)
            score_image   0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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