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COX14 COX14 TACO1 TACO1 MT-CO1 MT-CO1 MT-CO3 MT-CO3 COA4 COA4 MT-CO2 MT-CO2 COA3 COA3 UBC UBC FIG4 FIG4 SH3BGRL3 SH3BGRL3 TMEM62 TMEM62
"COA3" - cytochrome c oxidase assembly factor 3 in Homo sapiens
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Predicted Interactions
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COA3cytochrome c oxidase assembly factor 3; Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly (106 aa)    
Predicted Functional Partners:
TACO1
translational activator of mitochondrially encoded cytochrome c oxidase I; Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1 (297 aa)
        score_image   score_image   0.805
COA4
cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae); Putative COX assembly factor (By similarity) (87 aa)
            score_image   0.677
COX14
cytochrome c oxidase assembly homolog 14 (S. cerevisiae); Plays a role in the assembly or stability of the cytochrome c oxidase complex (COX). Requires for coordination of the early steps of COX assembly with the synthesis of MT-CO1 (57 aa)
      score_image score_image   score_image   0.657
MT-CO3
mitochondrially encoded cytochrome c oxidase III; Subunits I, II and III form the functional core of the enzyme complex (By similarity) (261 aa)
        score_image   score_image   0.618
MT-CO1
mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity) (513 aa)
        score_image   score_image   0.571
MT-CO2
mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (By similarity) (227 aa)
        score_image   score_image   0.566
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3; Could act as a modulator of glutaredoxin biological activity (93 aa)
            score_image   0.543
FIG4
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae); The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes (907 aa)
            score_image   0.541
TMEM62
transmembrane protein 62 (643 aa)
            score_image   0.528
UBC
ubiquitin C (685 aa)
        score_image       0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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