RASSF9 protein (Homo sapiens) - STRING network view

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RASSF9

Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity) (435 aa)

Predicted Functional Partners:

RASSF7

0.858

PAM

0.846

RAB11A

0.680

C12orf29

0.659

TP53BP2

0.639

PPP1R13B

0.639

PARD3

0.625

POC1B

0.621

CCDC85C

0.615

S100A7

0.615

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf29	POC1B	ENSP00000349358	ENSP00000323302	chromosome 12 open reading frame 29	POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis	0.660
C12orf29	RASSF9	ENSP00000349358	ENSP00000354884	chromosome 12 open reading frame 29	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.659
CCDC85C	PPP1R13B	ENSP00000369592	ENSP00000202556	coiled-coil domain containing 85C; May play an important role in cortical development, especially in the maintenance of radial glia (By similarity)	protein phosphatase 1, regulatory subunit 13B; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo	0.615
CCDC85C	RASSF9	ENSP00000369592	ENSP00000354884	coiled-coil domain containing 85C; May play an important role in cortical development, especially in the maintenance of radial glia (By similarity)	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.615
CCDC85C	TP53BP2	ENSP00000369592	ENSP00000341957	coiled-coil domain containing 85C; May play an important role in cortical development, especially in the maintenance of radial glia (By similarity)	tumor protein p53 binding protein, 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42	0.615
PAM	RASSF9	ENSP00000306100	ENSP00000354884	peptidylglycine alpha-amidating monooxygenase	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.846
PARD3	RASSF9	ENSP00000363921	ENSP00000354884	par-3 partitioning defective 3 homolog (C. elegans)	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.625
PARD3	TP53BP2	ENSP00000363921	ENSP00000341957	par-3 partitioning defective 3 homolog (C. elegans)	tumor protein p53 binding protein, 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42	0.635
POC1B	C12orf29	ENSP00000323302	ENSP00000349358	POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis	chromosome 12 open reading frame 29	0.660
POC1B	RASSF9	ENSP00000323302	ENSP00000354884	POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.621
PPP1R13B	CCDC85C	ENSP00000202556	ENSP00000369592	protein phosphatase 1, regulatory subunit 13B; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo	coiled-coil domain containing 85C; May play an important role in cortical development, especially in the maintenance of radial glia (By similarity)	0.615
PPP1R13B	RASSF7	ENSP00000202556	ENSP00000344226	protein phosphatase 1, regulatory subunit 13B; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization	0.639
PPP1R13B	RASSF9	ENSP00000202556	ENSP00000354884	protein phosphatase 1, regulatory subunit 13B; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.639
RAB11A	RASSF9	ENSP00000261890	ENSP00000354884	RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...]	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.680
RASSF7	PPP1R13B	ENSP00000344226	ENSP00000202556	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization	protein phosphatase 1, regulatory subunit 13B; Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo	0.639
RASSF7	RASSF9	ENSP00000344226	ENSP00000354884	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	0.858
RASSF7	S100A7	ENSP00000344226	ENSP00000357711	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization	S100 calcium binding protein A7	0.615
RASSF7	TP53BP2	ENSP00000344226	ENSP00000341957	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti- apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization	tumor protein p53 binding protein, 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42	0.639
RASSF9	C12orf29	ENSP00000354884	ENSP00000349358	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	chromosome 12 open reading frame 29	0.659
RASSF9	CCDC85C	ENSP00000354884	ENSP00000369592	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity)	coiled-coil domain containing 85C; May play an important role in cortical development, especially in the maintenance of radial glia (By similarity)	0.615

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