node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP4B1 | PMPCB | ENSP00000256658 | ENSP00000249269 | adaptor-related protein complex 4, beta 1 subunit; Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.544 |
AP4B1 | VEPH1 | ENSP00000256658 | ENSP00000354919 | adaptor-related protein complex 4, beta 1 subunit; Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.523 |
BAALC | DNASE1L1 | ENSP00000312457 | ENSP00000014935 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | deoxyribonuclease I-like 1 | 0.587 |
BAALC | VEPH1 | ENSP00000312457 | ENSP00000354919 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.523 |
CLCN7 | GPR144 | ENSP00000372193 | ENSP00000335156 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | G protein-coupled receptor 144; Orphan receptor | 0.478 |
CLCN7 | IFT140 | ENSP00000372193 | ENSP00000406012 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | 0.555 |
CLCN7 | OG12 | ENSP00000372193 | ENSP00000419362 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | short stature homeobox protein 2 isoform c ; May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation | 0.403 |
CLCN7 | TELO2 | ENSP00000372193 | ENSP00000262319 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | TEL2, telomere maintenance 2, homolog (S. cerevisiae); Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complex [...] | 0.612 |
CLCN7 | VEPH1 | ENSP00000372193 | ENSP00000354919 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.617 |
DNASE1L1 | BAALC | ENSP00000014935 | ENSP00000312457 | deoxyribonuclease I-like 1 | brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) | 0.587 |
DNASE1L1 | VEPH1 | ENSP00000014935 | ENSP00000354919 | deoxyribonuclease I-like 1 | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.661 |
GPR144 | CLCN7 | ENSP00000335156 | ENSP00000372193 | G protein-coupled receptor 144; Orphan receptor | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.478 |
GPR144 | TELO2 | ENSP00000335156 | ENSP00000262319 | G protein-coupled receptor 144; Orphan receptor | TEL2, telomere maintenance 2, homolog (S. cerevisiae); Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complex [...] | 0.501 |
GPR144 | VEPH1 | ENSP00000335156 | ENSP00000354919 | G protein-coupled receptor 144; Orphan receptor | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.512 |
IFT140 | CLCN7 | ENSP00000406012 | ENSP00000372193 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.555 |
IFT140 | OG12 | ENSP00000406012 | ENSP00000419362 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | short stature homeobox protein 2 isoform c ; May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation | 0.407 |
IFT140 | TELO2 | ENSP00000406012 | ENSP00000262319 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | TEL2, telomere maintenance 2, homolog (S. cerevisiae); Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complex [...] | 0.642 |
IFT140 | VEPH1 | ENSP00000406012 | ENSP00000354919 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | ventricular zone expressed PH domain homolog 1 (zebrafish) | 0.650 |
OG12 | CLCN7 | ENSP00000419362 | ENSP00000372193 | short stature homeobox protein 2 isoform c ; May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.403 |
OG12 | IFT140 | ENSP00000419362 | ENSP00000406012 | short stature homeobox protein 2 isoform c ; May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | 0.407 |