| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCY1 | ADCY8 | ENSP00000297323 | ENSP00000286355 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.910 |
| ADCY1 | APP | ENSP00000297323 | ENSP00000284981 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | amyloid beta (A4) precursor protein | 0.900 |
| ADCY1 | CNR1 | ENSP00000297323 | ENSP00000358511 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | cannabinoid receptor 1 (brain) | 0.900 |
| ADCY1 | DRD2 | ENSP00000297323 | ENSP00000354859 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.932 |
| ADCY1 | DRD3 | ENSP00000297323 | ENSP00000373169 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | dopamine receptor D3; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation | 0.900 |
| ADCY1 | DRD4 | ENSP00000297323 | ENSP00000176183 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | dopamine receptor D4 | 0.933 |
| ADCY1 | GRM3 | ENSP00000297323 | ENSP00000355316 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.923 |
| ADCY1 | HRH3 | ENSP00000297323 | ENSP00000342560 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | histamine receptor H3; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization | 0.903 |
| ADCY1 | HTR1A | ENSP00000297323 | ENSP00000316244 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity | 0.948 |
| ADCY8 | ADCY1 | ENSP00000286355 | ENSP00000297323 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 0.910 |
| ADCY8 | APP | ENSP00000286355 | ENSP00000284981 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | amyloid beta (A4) precursor protein | 0.900 |
| ADCY8 | CNR1 | ENSP00000286355 | ENSP00000358511 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | cannabinoid receptor 1 (brain) | 0.913 |
| ADCY8 | DRD2 | ENSP00000286355 | ENSP00000354859 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.906 |
| ADCY8 | DRD3 | ENSP00000286355 | ENSP00000373169 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | dopamine receptor D3; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation | 0.900 |
| ADCY8 | DRD4 | ENSP00000286355 | ENSP00000176183 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | dopamine receptor D4 | 0.900 |
| ADCY8 | GRM3 | ENSP00000286355 | ENSP00000355316 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.978 |
| ADCY8 | HRH3 | ENSP00000286355 | ENSP00000342560 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | histamine receptor H3; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization | 0.913 |
| ADCY8 | HTR1A | ENSP00000286355 | ENSP00000316244 | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity | 0.915 |
| APP | ADCY1 | ENSP00000284981 | ENSP00000297323 | amyloid beta (A4) precursor protein | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 0.900 |
| APP | ADCY8 | ENSP00000284981 | ENSP00000286355 | amyloid beta (A4) precursor protein | adenylate cyclase 8 (brain); This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | 0.900 |
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