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CSDC2 CSDC2 ROPN1 ROPN1 OLFM1 OLFM1 GJB3 GJB3 CNST CNST GJB6 GJB6 GJA1 GJA1 GJC1 GJC1 GJB2 GJB2 GJB1 GJB1 GGA2 GGA2
"CNST" - consortin, connexin sorting protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
CNSTconsortin, connexin sorting protein; Required for targeting of connexins to the plasma membrane (725 aa)    
Predicted Functional Partners:
GJB6
gap junction protein, beta 6, 30kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (261 aa)
        score_image   score_image   0.886
GJB2
gap junction protein, beta 2, 26kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) (226 aa)
        score_image   score_image   0.850
GJC1
gap junction protein, gamma 1, 45kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) (396 aa)
        score_image   score_image   0.747
GJB1
gap junction protein, beta 1, 32kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) (283 aa)
        score_image   score_image   0.702
GJA1
gap junction protein, alpha 1, 43kDa; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity- acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural s [...] (382 aa)
        score_image   score_image   0.689
GJB3
gap junction protein, beta 3, 31kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (270 aa)
        score_image       0.567
GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (613 aa)
        score_image   score_image   0.534
ROPN1
rhophilin associated tail protein 1 (212 aa)
        score_image       0.504
CSDC2
cold shock domain containing C2, RNA binding; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) (153 aa)
            score_image   0.492
OLFM1
olfactomedin 1; May play an important role in regulating the production of neural crest cells by the neural tube (By similarity) (467 aa)
            score_image   0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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