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UTP15 UTP15 WDR43 WDR43 WDR36 WDR36 HEATR1 HEATR1 BMS1 BMS1 TBL3 TBL3 WDR75 WDR75 UTP20 UTP20 PWP2 PWP2 WDR3 WDR3 NOL6 NOL6
"HEATR1" - HEAT repeat containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEATR1HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) (2144 aa)    
Predicted Functional Partners:
WDR36
WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 (951 aa)
      score_image score_image   score_image   0.999
PWP2
PWP2 periodic tryptophan protein homolog (yeast) (919 aa)
      score_image score_image   score_image   0.999
TBL3
transducin (beta)-like 3 (808 aa)
      score_image score_image   score_image   0.998
UTP20
UTP20, small subunit (SSU) processome component, homolog (yeast); Involved in 18S pre-rRNA processing. Associates with U3 snoRNA (2785 aa)
      score_image score_image   score_image   0.998
WDR75
WD repeat domain 75 (830 aa)
      score_image score_image   score_image   0.998
NOL6
nucleolar protein family 6 (RNA-associated) (1146 aa)
      score_image score_image   score_image   0.997
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (518 aa)
      score_image score_image   score_image   0.997
BMS1
BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (1282 aa)
      score_image score_image   score_image   0.997
WDR43
WD repeat domain 43 (677 aa)
      score_image score_image   score_image   0.997
WDR3
WD repeat domain 3 (943 aa)
      score_image score_image   score_image   0.996
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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