GNPAT protein (Homo sapiens) - STRING network view

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Score

GNPAT

glyceronephosphate O-acyltransferase (680 aa)

Predicted Functional Partners:

AGPS

0.978

FAR1

0.945

FAR2

0.930

GPD1

0.922

GPD2

0.922

GPD1L

0.917

DAK

0.800

PEX5

0.752

UBC

0.721

PEX7

0.663

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGPS	FAR1	ENSP00000264167	ENSP00000346874	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.932
AGPS	FAR2	ENSP00000264167	ENSP00000182377	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	fatty acyl CoA reductase 2; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18-1 and C18-2 but low activity can be observed with C10-C14 substrates	0.913
AGPS	GNPAT	ENSP00000264167	ENSP00000355607	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	glyceronephosphate O-acyltransferase	0.978
AGPS	PEX5	ENSP00000264167	ENSP00000407401	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	0.815
AGPS	UBC	ENSP00000264167	ENSP00000344818	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	ubiquitin C	0.825
DAK	GNPAT	ENSP00000378360	ENSP00000355607	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	glyceronephosphate O-acyltransferase	0.800
DAK	GPD1	ENSP00000378360	ENSP00000301149	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.829
DAK	GPD1L	ENSP00000378360	ENSP00000282541	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	glycerol-3-phosphate dehydrogenase 1-like; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L	0.829
DAK	GPD2	ENSP00000378360	ENSP00000308610	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	0.867
DAK	UBC	ENSP00000378360	ENSP00000344818	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	ubiquitin C	0.868
FAR1	AGPS	ENSP00000346874	ENSP00000264167	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.932
FAR1	GNPAT	ENSP00000346874	ENSP00000355607	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	glyceronephosphate O-acyltransferase	0.945
FAR1	UBC	ENSP00000346874	ENSP00000344818	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	ubiquitin C	0.923
FAR2	AGPS	ENSP00000182377	ENSP00000264167	fatty acyl CoA reductase 2; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18-1 and C18-2 but low activity can be observed with C10-C14 substrates	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.913
FAR2	GNPAT	ENSP00000182377	ENSP00000355607	fatty acyl CoA reductase 2; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18-1 and C18-2 but low activity can be observed with C10-C14 substrates	glyceronephosphate O-acyltransferase	0.930
GNPAT	AGPS	ENSP00000355607	ENSP00000264167	glyceronephosphate O-acyltransferase	alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity)	0.978
GNPAT	DAK	ENSP00000355607	ENSP00000378360	glyceronephosphate O-acyltransferase	dihydroxyacetone kinase 2 homolog (S. cerevisiae); Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate	0.800
GNPAT	FAR1	ENSP00000355607	ENSP00000346874	glyceronephosphate O-acyltransferase	fatty acyl CoA reductase 1; Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols	0.945
GNPAT	FAR2	ENSP00000355607	ENSP00000182377	glyceronephosphate O-acyltransferase	fatty acyl CoA reductase 2; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18-1 and C18-2 but low activity can be observed with C10-C14 substrates	0.930
GNPAT	GPD1	ENSP00000355607	ENSP00000301149	glyceronephosphate O-acyltransferase	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.922

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