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DBI DBI TGOLN2 TGOLN2 ACBD6 ACBD6 UBC UBC GOLGB1 GOLGB1 PI4KB PI4KB ACBD3 ACBD3 GOLGA3 GOLGA3 EPRS EPRS RASD1 RASD1 BPNT1 BPNT1
"ACBD3" - acyl-CoA binding domain containing 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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ACBD3acyl-CoA binding domain containing 3; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity) (528 aa)    
Predicted Functional Partners:
GOLGA3
golgin A3; Golgi auto-antigen; probably involved in maintaining Golgi structure (1498 aa)
        score_image   score_image   0.945
UBC
ubiquitin C (685 aa)
        score_image       0.921
GOLGB1
golgin B1; May participate in forming intercisternal cross-bridges of the Golgi complex (3259 aa)
        score_image   score_image   0.861
RASD1
RAS, dexamethasone-induced 1; Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity) (281 aa)
            score_image   0.843
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity) (828 aa)
      score_image score_image   score_image   0.773
EPRS
glutamyl-prolyl-tRNA synthetase (1512 aa)
            score_image   0.759
BPNT1
3’(2’), 5’-bisphosphate nucleotidase 1; Converts adenosine 3’-phosphate 5’-phosphosulfate (PAPS) to adenosine 5’-phosphosulfate (APS) and 3’(2’)-phosphoadenosine 5’- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4- trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6 (308 aa)
            score_image   0.751
DBI
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (148 aa)
            score_image   0.694
ACBD6
acyl-CoA binding domain containing 6; Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18-1-CoA, lower affinity for unsaturated C20-4-CoA, and very weak affinity for saturated C16-0- CoA. Does not bind fatty acids (282 aa)
            score_image   0.655
TGOLN2
trans-golgi network protein 2 (453 aa)
        score_image   score_image   0.603
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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