RPS6KC1 protein (Homo sapiens) - STRING network view

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RPS6KC1

ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (1066 aa)

Predicted Functional Partners:

SPHK1

0.945

PRDX3

0.940

PRDX2

0.817

UBC

0.620

PBX2

0.615

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PBX2	RPS6KC1	ENSP00000364190	ENSP00000355927	pre-B-cell leukemia homeobox 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	0.615
PRDX2	RPS6KC1	ENSP00000301522	ENSP00000355927	peroxiredoxin 2; Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	0.817
PRDX2	UBC	ENSP00000301522	ENSP00000344818	peroxiredoxin 2; Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)	ubiquitin C	0.967
PRDX3	RPS6KC1	ENSP00000298510	ENSP00000355927	peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	0.940
PRDX3	UBC	ENSP00000298510	ENSP00000344818	peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol	ubiquitin C	0.874
RPS6KC1	PBX2	ENSP00000355927	ENSP00000364190	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	pre-B-cell leukemia homeobox 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1	0.615
RPS6KC1	PRDX2	ENSP00000355927	ENSP00000301522	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	peroxiredoxin 2; Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)	0.817
RPS6KC1	PRDX3	ENSP00000355927	ENSP00000298510	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol	0.940
RPS6KC1	SPHK1	ENSP00000355927	ENSP00000313681	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol	0.945
RPS6KC1	UBC	ENSP00000355927	ENSP00000344818	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	ubiquitin C	0.620
SPHK1	RPS6KC1	ENSP00000313681	ENSP00000355927	sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	0.945
SPHK1	UBC	ENSP00000313681	ENSP00000344818	sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol	ubiquitin C	0.802
UBC	PRDX2	ENSP00000344818	ENSP00000301522	ubiquitin C	peroxiredoxin 2; Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)	0.967
UBC	PRDX3	ENSP00000344818	ENSP00000298510	ubiquitin C	peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol	0.874
UBC	RPS6KC1	ENSP00000344818	ENSP00000355927	ubiquitin C	ribosomal protein S6 kinase, 52kDa, polypeptide 1; May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell	0.620
UBC	SPHK1	ENSP00000344818	ENSP00000313681	ubiquitin C	sphingosine kinase 1; Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol	0.802

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