SERTAD4 protein (Homo sapiens) - STRING network view

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Score

SERTAD4

SERTA domain containing 4 (356 aa)

Predicted Functional Partners:

PPP2R1A

0.731

PRPF38B

0.641

CCDC3

0.630

PPP2R2B

0.615

AKT1

0.463

RPUSD3

0.411

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	PPP2R1A	ENSP00000270202	ENSP00000324804	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	0.985
AKT1	PPP2R2B	ENSP00000270202	ENSP00000336591	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	protein phosphatase 2, regulatory subunit B, beta	0.904
AKT1	SERTAD4	ENSP00000270202	ENSP00000355979	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	SERTA domain containing 4	0.463
CCDC3	SERTAD4	ENSP00000368102	ENSP00000355979	coiled-coil domain containing 3	SERTA domain containing 4	0.630
PPP2R1A	AKT1	ENSP00000324804	ENSP00000270202	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	0.985
PPP2R1A	PPP2R2B	ENSP00000324804	ENSP00000336591	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	protein phosphatase 2, regulatory subunit B, beta	0.998
PPP2R1A	SERTAD4	ENSP00000324804	ENSP00000355979	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	SERTA domain containing 4	0.731
PPP2R2B	AKT1	ENSP00000336591	ENSP00000270202	protein phosphatase 2, regulatory subunit B, beta	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	0.904
PPP2R2B	PPP2R1A	ENSP00000336591	ENSP00000324804	protein phosphatase 2, regulatory subunit B, beta	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	0.998
PPP2R2B	SERTAD4	ENSP00000336591	ENSP00000355979	protein phosphatase 2, regulatory subunit B, beta	SERTA domain containing 4	0.615
PRPF38B	RPUSD3	ENSP00000359042	ENSP00000373331	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	RNA pseudouridylate synthase domain containing 3	0.449
PRPF38B	SERTAD4	ENSP00000359042	ENSP00000355979	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	SERTA domain containing 4	0.641
RPUSD3	PRPF38B	ENSP00000373331	ENSP00000359042	RNA pseudouridylate synthase domain containing 3	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.449
RPUSD3	SERTAD4	ENSP00000373331	ENSP00000355979	RNA pseudouridylate synthase domain containing 3	SERTA domain containing 4	0.411
SERTAD4	AKT1	ENSP00000355979	ENSP00000270202	SERTA domain containing 4	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	0.463
SERTAD4	CCDC3	ENSP00000355979	ENSP00000368102	SERTA domain containing 4	coiled-coil domain containing 3	0.630
SERTAD4	PPP2R1A	ENSP00000355979	ENSP00000324804	SERTA domain containing 4	protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis	0.731
SERTAD4	PPP2R2B	ENSP00000355979	ENSP00000336591	SERTA domain containing 4	protein phosphatase 2, regulatory subunit B, beta	0.615
SERTAD4	PRPF38B	ENSP00000355979	ENSP00000359042	SERTA domain containing 4	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.641
SERTAD4	RPUSD3	ENSP00000355979	ENSP00000373331	SERTA domain containing 4	RNA pseudouridylate synthase domain containing 3	0.411

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