SWT1 protein (Homo sapiens) - STRING network view

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SWT1

SWT1 RNA endoribonuclease homolog (S. cerevisiae) (900 aa)

Predicted Functional Partners:

THOC2

0.746

ZC3H13

0.686

C6orf70

0.506

DDX39B

0.502

DDX39A

0.491

TJAP1

0.465

TTC40

0.412

NOB1

0.405

ALYREF

0.403

POLDIP3

0.403

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALYREF	DDX39A	ENSP00000421592	ENSP00000242776	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	0.995
ALYREF	DDX39B	ENSP00000421592	ENSP00000379475	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.960
ALYREF	SWT1	ENSP00000421592	ENSP00000356470	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	0.403
ALYREF	THOC2	ENSP00000421592	ENSP00000245838	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	THO complex 2; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex [...]	0.999
ALYREF	ZC3H13	ENSP00000421592	ENSP00000282007	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	zinc finger CCCH-type containing 13	0.992
C6orf70	SWT1	ENSP00000355735	ENSP00000356470	chromosome 6 open reading frame 70	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	0.506
DDX39A	ALYREF	ENSP00000242776	ENSP00000421592	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	0.995
DDX39A	DDX39B	ENSP00000242776	ENSP00000379475	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.632
DDX39A	POLDIP3	ENSP00000242776	ENSP00000252115	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	polymerase (DNA-directed), delta interacting protein 3	0.825
DDX39A	SWT1	ENSP00000242776	ENSP00000356470	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	0.491
DDX39A	THOC2	ENSP00000242776	ENSP00000245838	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	THO complex 2; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex [...]	0.932
DDX39A	ZC3H13	ENSP00000242776	ENSP00000282007	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	zinc finger CCCH-type containing 13	0.758
DDX39B	ALYREF	ENSP00000379475	ENSP00000421592	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	Aly/REF export factor; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO [...]	0.960
DDX39B	DDX39A	ENSP00000379475	ENSP00000242776	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus	0.632
DDX39B	POLDIP3	ENSP00000379475	ENSP00000252115	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	polymerase (DNA-directed), delta interacting protein 3	0.831
DDX39B	SWT1	ENSP00000379475	ENSP00000356470	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	0.502
DDX39B	THOC2	ENSP00000379475	ENSP00000245838	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	THO complex 2; Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex [...]	0.996
DDX39B	ZC3H13	ENSP00000379475	ENSP00000282007	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	zinc finger CCCH-type containing 13	0.758
NOB1	SWT1	ENSP00000268802	ENSP00000356470	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); May play a role in mRNA degradation	SWT1 RNA endoribonuclease homolog (S. cerevisiae)	0.405
NOB1	TJAP1	ENSP00000268802	ENSP00000361522	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); May play a role in mRNA degradation	tight junction associated protein 1 (peripheral)	0.506

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