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STRINGSTRING
SLC29A3 SLC29A3 FHL2 FHL2 FOXK1 FOXK1 ZBTB43 ZBTB43 FAM129A FAM129A POLD2 POLD2 UBC UBC NPM1 NPM1 AKT1 AKT1 CPVL CPVL LECT1 LECT1
"FAM129A" - family with sequence similarity 129, member A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
FAM129Afamily with sequence similarity 129, member A; Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity) (928 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.620
CPVL
carboxypeptidase, vitellogenic-like; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation (476 aa)
            score_image   0.597
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin) (294 aa)
        score_image   score_image   0.568
AKT1
v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...] (480 aa)
        score_image   score_image   0.564
POLD2
polymerase (DNA directed), delta 2, accessory subunit; The function of the small subunit is not yet clear (469 aa)
        score_image       0.538
FOXK1
forkhead box K1; Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity) (733 aa)
        score_image       0.538
FHL2
four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation (279 aa)
        score_image       0.524
LECT1
leukocyte cell derived chemotaxin 1; Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (334 aa)
            score_image   0.502
ZBTB43
zinc finger and BTB domain containing 43; May be involved in transcriptional regulation (467 aa)
            score_image   0.439
SLC29A3
solute carrier family 29 (nucleoside transporters), member 3 (475 aa)
            score_image   0.438
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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