| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCT7 | CCT8 | ENSP00000258091 | ENSP00000286788 | chaperonin containing TCP1, subunit 7 (eta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) | chaperonin containing TCP1, subunit 8 (theta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | 0.999 |
| CCT7 | IER5 | ENSP00000258091 | ENSP00000356549 | chaperonin containing TCP1, subunit 7 (eta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) | immediate early response 5 | 0.453 |
| CCT8 | CCT7 | ENSP00000286788 | ENSP00000258091 | chaperonin containing TCP1, subunit 8 (theta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | chaperonin containing TCP1, subunit 7 (eta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) | 0.999 |
| CCT8 | IER5 | ENSP00000286788 | ENSP00000356549 | chaperonin containing TCP1, subunit 8 (theta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | immediate early response 5 | 0.504 |
| CDC25B | ETS1 | ENSP00000245960 | ENSP00000376436 | cell division cycle 25 homolog B (S. pombe) | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | 0.699 |
| CDC25B | IER5 | ENSP00000245960 | ENSP00000356549 | cell division cycle 25 homolog B (S. pombe) | immediate early response 5 | 0.814 |
| ETS1 | CDC25B | ENSP00000376436 | ENSP00000245960 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | cell division cycle 25 homolog B (S. pombe) | 0.699 |
| ETS1 | IER5 | ENSP00000376436 | ENSP00000356549 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | immediate early response 5 | 0.483 |
| ETS1 | TAL1 | ENSP00000376436 | ENSP00000294339 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.709 |
| IER5 | CCT7 | ENSP00000356549 | ENSP00000258091 | immediate early response 5 | chaperonin containing TCP1, subunit 7 (eta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity) | 0.453 |
| IER5 | CCT8 | ENSP00000356549 | ENSP00000286788 | immediate early response 5 | chaperonin containing TCP1, subunit 8 (theta); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin | 0.504 |
| IER5 | CDC25B | ENSP00000356549 | ENSP00000245960 | immediate early response 5 | cell division cycle 25 homolog B (S. pombe) | 0.814 |
| IER5 | ETS1 | ENSP00000356549 | ENSP00000376436 | immediate early response 5 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion | 0.483 |
| IER5 | LCMT2 | ENSP00000356549 | ENSP00000307214 | immediate early response 5 | leucine carboxyl methyltransferase 2; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues | 0.507 |
| IER5 | MPDZ | ENSP00000356549 | ENSP00000370410 | immediate early response 5 | multiple PDZ domain protein | 0.750 |
| IER5 | MYCL1 | ENSP00000356549 | ENSP00000380494 | immediate early response 5 | v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) | 0.512 |
| IER5 | PDZK1IP1 | ENSP00000356549 | ENSP00000294338 | immediate early response 5 | PDZK1 interacting protein 1; May play an important role in tumor biology | 0.608 |
| IER5 | TAL1 | ENSP00000356549 | ENSP00000294339 | immediate early response 5 | T-cell acute lymphocytic leukemia 1; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity) | 0.499 |
| IER5 | TAL2 | ENSP00000356549 | ENSP00000334547 | immediate early response 5 | T-cell acute lymphocytic leukemia 2 | 0.487 |
| LCMT2 | IER5 | ENSP00000307214 | ENSP00000356549 | leucine carboxyl methyltransferase 2; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues | immediate early response 5 | 0.507 |
Share
