Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | C1orf110 | chromosome 1 open reading frame 110 (302 aa) | ||||||||||||
Predicted Functional Partners:
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 | LRRC71 | leucine rich repeat containing 71 (559 aa) |
 |
0.700 | ||||||||||
 | C22orf15 | chromosome 22 open reading frame 15 (148 aa) |
|
0.646 | ||||||||||
 | FAM216B | family with sequence similarity 216, member B (139 aa) |
|
0.646 | ||||||||||
 | C6orf118 | chromosome 6 open reading frame 118 (469 aa) |
|
0.635 | ||||||||||
 | WDR96 | WD repeat domain 96 (1665 aa) |
|
0.626 | ||||||||||
 | C8orf40 | chromosome 8 open reading frame 40 (107 aa) |
|
0.622 | ||||||||||
 | C16orf46 | chromosome 16 open reading frame 46 (395 aa) |
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0.567 | ||||||||||
 | CYSTM1 | cysteine-rich transmembrane module containing 1 (97 aa) |
|
0.501 | ||||||||||
 | ARMC3 | armadillo repeat containing 3 (872 aa) |
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0.471 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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