node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RHO | TAAR2 | ENSP00000296271 | ENSP00000356908 | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | trace amine associated receptor 2; Orphan receptor | 0.439 |
RHO | TAS1R1 | ENSP00000296271 | ENSP00000331867 | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | taste receptor, type 1, member 1 | 0.403 |
RHO | TAS1R3 | ENSP00000296271 | ENSP00000344411 | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | 0.426 |
STX7 | TAAR2 | ENSP00000356918 | ENSP00000356908 | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes | trace amine associated receptor 2; Orphan receptor | 0.649 |
STX7 | VNN1 | ENSP00000356918 | ENSP00000356905 | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes | vanin 1; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine | 0.640 |
STX7 | VNN3 | ENSP00000356918 | ENSP00000440594 | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes | vanin 3 | 0.605 |
TAAR2 | RHO | ENSP00000356908 | ENSP00000296271 | trace amine associated receptor 2; Orphan receptor | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | 0.439 |
TAAR2 | STX7 | ENSP00000356908 | ENSP00000356918 | trace amine associated receptor 2; Orphan receptor | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes | 0.649 |
TAAR2 | TAS1R1 | ENSP00000356908 | ENSP00000331867 | trace amine associated receptor 2; Orphan receptor | taste receptor, type 1, member 1 | 0.414 |
TAAR2 | TAS1R3 | ENSP00000356908 | ENSP00000344411 | trace amine associated receptor 2; Orphan receptor | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | 0.428 |
TAAR2 | VNN1 | ENSP00000356908 | ENSP00000356905 | trace amine associated receptor 2; Orphan receptor | vanin 1; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine | 0.544 |
TAAR2 | VNN3 | ENSP00000356908 | ENSP00000440594 | trace amine associated receptor 2; Orphan receptor | vanin 3 | 0.495 |
TAS1R1 | RHO | ENSP00000331867 | ENSP00000296271 | taste receptor, type 1, member 1 | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | 0.403 |
TAS1R1 | TAAR2 | ENSP00000331867 | ENSP00000356908 | taste receptor, type 1, member 1 | trace amine associated receptor 2; Orphan receptor | 0.414 |
TAS1R1 | TAS1R3 | ENSP00000331867 | ENSP00000344411 | taste receptor, type 1, member 1 | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | 0.963 |
TAS1R3 | RHO | ENSP00000344411 | ENSP00000296271 | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal | 0.426 |
TAS1R3 | TAAR2 | ENSP00000344411 | ENSP00000356908 | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | trace amine associated receptor 2; Orphan receptor | 0.428 |
TAS1R3 | TAS1R1 | ENSP00000344411 | ENSP00000331867 | taste receptor, type 1, member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses | taste receptor, type 1, member 1 | 0.963 |
VNN1 | STX7 | ENSP00000356905 | ENSP00000356918 | vanin 1; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine | syntaxin 7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes | 0.640 |
VNN1 | TAAR2 | ENSP00000356905 | ENSP00000356908 | vanin 1; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine | trace amine associated receptor 2; Orphan receptor | 0.544 |