| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCL9 | FCRL1 | ENSP00000234739 | ENSP00000357158 | B-cell CLL/lymphoma 9 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.483 |
| C12orf55 | FCRL1 | ENSP00000431759 | ENSP00000357158 | chromosome 12 open reading frame 55 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.472 |
| C12orf55 | TMEM156 | ENSP00000431759 | ENSP00000371364 | chromosome 12 open reading frame 55 | transmembrane protein 156 | 0.658 |
| FCAMR | FCRL1 | ENSP00000316491 | ENSP00000357158 | Fc receptor, IgA, IgM, high affinity; Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.472 |
| FCGR2A | FCGR3A | ENSP00000271450 | ENSP00000356946 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | 0.916 |
| FCGR2A | FCRL1 | ENSP00000271450 | ENSP00000357158 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.608 |
| FCGR2A | PIGR | ENSP00000271450 | ENSP00000348888 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment | 0.609 |
| FCGR2A | SULT2B1 | ENSP00000271450 | ENSP00000201586 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol | 0.560 |
| FCGR2B | FCGR3A | ENSP00000351497 | ENSP00000356946 | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | 0.914 |
| FCGR2B | FCRL1 | ENSP00000351497 | ENSP00000357158 | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.562 |
| FCGR3A | FCGR2A | ENSP00000356946 | ENSP00000271450 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | 0.916 |
| FCGR3A | FCGR2B | ENSP00000356946 | ENSP00000351497 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | 0.914 |
| FCGR3A | FCRL1 | ENSP00000356946 | ENSP00000357158 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | 0.651 |
| FCGR3A | PIGR | ENSP00000356946 | ENSP00000348888 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment | 0.683 |
| FCGR3A | SULT2B1 | ENSP00000356946 | ENSP00000201586 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol | 0.439 |
| FCRL1 | BCL9 | ENSP00000357158 | ENSP00000234739 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | B-cell CLL/lymphoma 9 | 0.483 |
| FCRL1 | C12orf55 | ENSP00000357158 | ENSP00000431759 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | chromosome 12 open reading frame 55 | 0.472 |
| FCRL1 | FCAMR | ENSP00000357158 | ENSP00000316491 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | Fc receptor, IgA, IgM, high affinity; Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM | 0.472 |
| FCRL1 | FCGR2A | ENSP00000357158 | ENSP00000271450 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | 0.608 |
| FCRL1 | FCGR2B | ENSP00000357158 | ENSP00000351497 | Fc receptor-like 1; May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | 0.562 |
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